Evidence supporting the use of: Black Seed
For the health condition: Acne

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Black seed (Nigella sativa), also known as black cumin, has a long history of use in traditional medicine systems, particularly in the Middle East, Asia, and North Africa. For acne, its use is primarily traditional rather than strongly supported by modern science. Historical texts and folk remedies have employed black seed oil topically for various skin ailments, including acne, due to its reputed anti-inflammatory and antimicrobial properties. The active compound thymoquinone is thought to play a role in reducing inflammation and possibly inhibiting the growth of acne-causing bacteria.

Scientific validation is limited: a few small studies and case reports suggest that topical Nigella sativa oil may improve acne severity, possibly due to its anti-inflammatory and antibacterial actions. For example, one small randomized study compared a cream containing black seed oil to benzoyl peroxide and found both to be effective for mild to moderate acne, though the study’s sample size was small and methodology limited. Systematic reviews and larger clinical trials are lacking. Thus, while there is some preliminary evidence, it remains insufficient to fully substantiate its efficacy. Most of the support for black seed’s use in treating acne comes from traditional usage patterns rather than robust clinical evidence.

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Products containing Black Seed

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