Evidence supporting the use of: Black Seed
For the health condition: Acne
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Black seed (Nigella sativa), also known as black cumin, has a long history of use in traditional medicine systems, particularly in the Middle East, Asia, and North Africa. For acne, its use is primarily traditional rather than strongly supported by modern science. Historical texts and folk remedies have employed black seed oil topically for various skin ailments, including acne, due to its reputed anti-inflammatory and antimicrobial properties. The active compound thymoquinone is thought to play a role in reducing inflammation and possibly inhibiting the growth of acne-causing bacteria.
Scientific validation is limited: a few small studies and case reports suggest that topical Nigella sativa oil may improve acne severity, possibly due to its anti-inflammatory and antibacterial actions. For example, one small randomized study compared a cream containing black seed oil to benzoyl peroxide and found both to be effective for mild to moderate acne, though the study’s sample size was small and methodology limited. Systematic reviews and larger clinical trials are lacking. Thus, while there is some preliminary evidence, it remains insufficient to fully substantiate its efficacy. Most of the support for black seed’s use in treating acne comes from traditional usage patterns rather than robust clinical evidence.
Other ingredients used for Acne
ajoenealoe vera
alpha-pinene
berberine
bisabolol
black cumin
burdock
bасора
cannabis sativa oil
chamomile
cucumber
turmeric
curcumin
DIM (diindolylmethane)
epigallocatechin gallate (EGCG)
evening primrose oil
garlic bulb
green tea
hemp oil
honeysuckle
l-cystine
lactobacillus acidophilus
lactobacillus casei
lactobacillus reuteri
lactobacillus rhamnosus
lactoperoxidase
lauric acid
lavender
licorice root
monolaurin
niacinamide (vitamin B3)
omega-3 fatty acids
omega-6 fatty acids
oregon grape
pantothenic acid (vitamin B5)
phenolic acids
scrophularia root
sphaeranthus indicus
thyme
tomato
vitamin A
vitamin B
vitamin C
vitamin D
vitamin E
seaweed
zinc
shen-chu
neem tree
paederia foetida
tinospora cordifolia
blackboard tree
chrysanthemum
morinda
oriental arborvitae
trace minerals
anemarrhena asphodeloides
fulvic acid
herbal blend (proprietary)
melaleuca alternifolia
indigo leaves
15,16-Dihydrotanshinone I
Ash
Apple Cider Vinegar
Alpha-terpineol
Azelaic acid
Allicin
Abrus
Andrographolide
Alpha Hydroxy Acids
Allantoin
Asteracea
Argan nut oil
Anemarrhena
Bee Propolis
Black Seed
Babchi
Baphicacanthus cusia
Bidens pilosa
Banyan
Bee products
Bassia scoparia
Coconut
Caryophyllene
Calendula
Chlorophyllin
Carvacrol
Curcuminoid
Chinese Raisintree
Curcumen
Centipeda
Curcuma
Chinatree
Castile Soap
Copaiba Oil
Clerodendrum indicum
Cannabichromene
Cannabigerol
Dianthus
Eclipta
Evening Primrose
Other health conditions supported by Black Seed
AcneAllergies (respiratory)
Alzheimer's Disease
Anxiety
Arthritis
Asthma
Autoimmune Disorders
Blood Poisoning
Bronchitis
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Cholesterol (high)
Colds (antiviral)
Colds (general)
Colds (prevention)
Congestion (bronchial)
Congestion (lungs)
Congestion (sinus)
Congestive Heart Failure
Constipation (adults)
Constipation (children)
Cough (dry)
Cough (general)
Cough (spastic)
Diabetes
Diarrhea
Digestion (poor)
Dyspepsia
Eczema
Epilepsy
Fatigue
Fever
Gastritis
Gingivitis
Hair (loss or thinning)
Headache (general)
Headache (sinus)
Headache (tension)
Heart (weakness)
Hepatitis
Hypertension
Inflammation
Influenza
Insomnia
Liver Detoxification
Lupus
Malaria
Memory and Brain Function
Menopause
Migraine
Nausea and Vomiting