Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Baphicacanthus cusia, commonly known as "Qing Dai" or "Indigo naturalis," has a longstanding history of use in traditional Chinese medicine (TCM) to address various skin conditions, including acne. The traditional rationale for its use is based on its purported abilities to "clear heat," "detoxify," and reduce inflammation—concepts central to TCM's approach to treating inflammatory skin disorders. It is often included in topical preparations or sometimes as part of oral formulations targeting skin eruptions, ulcers, and pustules, which are interpreted in TCM as manifestations of "heat" or "toxic" conditions. While some preliminary laboratory and small-scale clinical studies have suggested Baphicacanthus cusia possesses anti-inflammatory and antimicrobial properties, direct, robust scientific evidence supporting its use for acne vulgaris specifically is limited. The majority of support for its use in acne comes from historical texts, practitioner reports, and its inclusion in classic TCM formulae for dermatological conditions. Therefore, its application for acne is justified primarily by tradition rather than by high-quality, modern clinical trials. The evidence rating is 2, reflecting a low-to-moderate degree of support based mostly on traditional practice and limited early-phase research, but lacking large, well-controlled studies in acne patients specifically.

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