Lemon balm (Melissa officinalis) has a long history of use in traditional herbal medicine, particularly for its calming and mood-supportive properties. While it is commonly used to support cognitive function, memory, and relaxation, the specific claim that it supports the "Acetylcholine body system" is primarily rooted in traditional knowledge rather than direct scientific validation. Traditional use often centers on lemon balm's reputed benefits for the nervous system and mental clarity, which are indirectly related to acetylcholine, a key neurotransmitter involved in memory and learning.

Some preliminary research suggests that lemon balm may inhibit acetylcholinesterase, the enzyme that breaks down acetylcholine, theoretically leading to increased acetylcholine levels. However, clinical evidence is limited and largely confined to small-scale studies or in vitro experiments. Most of the available research focuses on lemon balm’s anxiolytic (anxiety-reducing) and mild cognitive-enhancing effects, with only tangential reference to acetylcholine.

In summary, lemon balm’s use for supporting the acetylcholine system is based more on traditional applications for cognitive and nervous system health than on robust scientific evidence directly linking it to acetylcholine modulation. The current scientific support for this specific use is limited and not yet conclusive.