Evidence supporting the use of: Panthenol
For the health condition: Abrasions
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Panthenol, also known as provitamin B5, is commonly used in topical formulations for skin abrasions due to its hydrating and barrier-supporting properties. Scientific evidence indicates that panthenol promotes wound healing, primarily by enhancing fibroblast proliferation, supporting epithelialization, and maintaining skin hydration, which are essential for effective repair of superficial wounds like abrasions.
Several in vitro and in vivo studies have demonstrated that panthenol can accelerate the closure of minor wounds and abrasions. For example, clinical trials have shown that topical panthenol leads to improved stratum corneum hydration and a reduction in skin irritation, which may indirectly facilitate faster healing of abrasions. A randomized controlled trial published in Cutaneous and Ocular Toxicology (2014) found that a dexpanthenol-containing ointment significantly improved wound healing compared to placebo in patients with superficial skin injuries.
While panthenol is not considered a primary wound-healing agent like some advanced dressings or prescription medications, its favorable safety profile and evidence of supporting re-epithelialization and reducing transepidermal water loss make it a scientifically justified supportive treatment for minor abrasions. However, the strength of evidence is moderate (rated 3/5), as most studies are small or focus on surrogate markers such as hydration and irritation rather than hard clinical outcomes.
Other ingredients used for Abrasions
AbrusAbuta
Acacia
Achyranthes
Agave
Agrimony
Ajuga
Alchemilla
Alchornea
Alkanet
Alkanna
Allantoin
Aloe vera
Alstonia scholaris
Ampelopsis
anamu
Antirrhinum majus
Aquilegia formosa
arnica
ash
asiaticoside
assam indigo
avens
bai ji
balsam
banyan
Barleria
bee hive
bee products
bee propolis
benzoin
bindweed
blackbrush
blackthorn
Bletilla
bloodroot
Boerhavia diffusa
Bombax
boxthorne
Brazilian peppertree
Butea monosperma
Calendula
Calochortus
Calotropis gigantea
capillary artemisia
carrapichinho
Casearia sylvestris
castile soap
cattail
Cedrus libani
celandine
Centella asiatica
Centella triterpenes
Centipeda
chamomile
chickweed
cinquefoil
Clerodendrum indicum
cocklebur
cocoa butter
colloidal silver
comfrey
cornflower
cowherb
Cymbidium goeringii
Cynanchum
Cynodon dactylon
Davilla rugosa
Didymocarpus
dragon\'s blood
elephant vine
elephant\'s head
English elm
Epidermal Growth Factor
Erigeron
Erodium cicutarium
Euphorbia
fibrinase
fibroblast growth factor
ficin
fir
Flueggea suffruticosa
Fomes fomentarius
Gambir
Genipa americana
genipap
geranium
Gnaphalium
golden shower tree
goldenseal
gotu kola
Gugambilla
heal-all
henna
honey
hyaluronic acid
Hydrocolloid
Immortelle
impatiens
iridoid glycosides
Jessica\'s sticktight
jojoba oil
Kalanchoe pinnatum
Kigelia africana
lac resin
lacquertree
Lantana camara
lavender
Leptospermum scoparium
Lesser speargrass
licorice root
Lilium polyphyllum
little ironweed
lodhtree
Lophira lanceolata
Lygodium
Macaranga indica
Mahonia
Malva sylvestris
marigold
Maritime Dock
Marking Nut Tree
Matico
melaleuca alternifolia
Microbial enzymes (proprietary)
Milkweed
Moss
Mountain horopito
Mucin
Myrrh
Nimbidin
nut grass
Oak
oriental arborvitae
Oxystelma
paederia foetida
Panthenol
paw paw
Plantago
plantain
Plumbago zeylanica
Povidone
Prolase
Propolis
protease
purified silver
purple Tephrosia
red alder
red spiderling
resin
Rhus glabra
Rosa californica
Sanguisorba
Sanicle
Sapindus mukorossi
sea salt
Self-Heal
Sensitive Plant
Sericin
Sesbania
shen-chu
Shikonin
Sickle-leaf hare's ear
siler root
Silverweed
slippery elm bark
Smoketree
Smooth Alder
Spanish Needle
Speedwell
Stellaria dichotoma
Stereospermum
Tagetes
Tannins
Tea Tree Oil
Thymol
Tridax
Trumpet Vine
turmeric
vitamin C
Waltheria ovata
White oak
Whiteweed
Witch Hazel
xanthium (cockleburs)
Yarrow
Yerba Mansa
Zinc
Other health conditions supported by Panthenol
AbrasionsBlisters
Burns and Scalds
Cuts
Dermatitis
Diaper Rash
Eczema
Lesions
Scratches and Abrasions
Scars / Scar Tissue
Skin (dry and/or flaky)
Skin Care (general)
Sunburn
Wounds and Sores
