Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Nimbidin is a major active compound isolated from the seeds of the neem tree (Azadirachta indica). Its use in treating abrasions is primarily justified by traditional medicine systems, particularly Ayurveda and folk medicine in South Asia. Historically, neem extracts and their constituents, including nimbidin, have been used topically to manage minor wounds, abrasions, and skin infections due to their reputed antimicrobial and anti-inflammatory properties.

While there is some laboratory evidence indicating that nimbidin exhibits antibacterial and anti-inflammatory activity in vitro and in animal models, direct clinical evidence supporting its efficacy specifically for treating abrasions in humans is limited. Most available studies are preclinical and do not focus on abrasions per se, but rather on general wound healing or skin infections. Therefore, the traditional use is partially supported by these mechanistic studies, but robust clinical trials in humans are lacking.

In summary, nimbidin’s use for abrasions is rooted in traditional practices and partially supported by preliminary scientific investigations, but the overall strength of evidence remains low due to a lack of targeted clinical research.

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More about Abrasions

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