Evidence supporting the use of: Hydrogen peroxide
For the health condition: Abrasions
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Hydrogen peroxide has been traditionally used as an antiseptic for treating minor abrasions and wounds. Its application is based on its ability to release oxygen when it comes into contact with tissue, producing effervescence that was believed to help mechanically remove debris and kill bacteria. Historically, it became popular in the early 20th century as a household antiseptic, and its use persists in first aid kits globally.
However, scientific evidence for its efficacy in wound healing is limited. Studies have shown that while hydrogen peroxide does have antimicrobial properties, it is also cytotoxic—that is, it can damage healthy cells required for healing, particularly fibroblasts and keratinocytes. This cytotoxicity can delay the healing process and potentially worsen outcomes compared to saline or other gentler cleansers. Modern wound care guidelines generally advise against the routine use of hydrogen peroxide for abrasions, favoring milder, non-cytotoxic solutions unless debris removal is essential and no alternatives are available. Despite this, its use persists, largely due to tradition and the visible "bubbling" effect, which gives the impression of cleaning. In summary, hydrogen peroxide’s use for abrasions is justified more by tradition than robust scientific validation, and its evidence rating for this indication remains low.
Other ingredients used for Abrasions
aloe verabeeswax
bisabolol
chamomile
turmeric
glycerin
goldenseal
gotu kola
hyaluronic acid
lavender
licorice root
microbial enzymes (proprietary)
mucin
plantain
protease
purified silver
slippery elm bark
vitamin C
zinc
chickweed
xanthium (cockleburs)
shen-chu
nut grass
clerodendrum indicum
paederia foetida
boxthorne
yarrow
moss
myrrh
siler root
oriental arborvitae
assam indigo
paw paw
white oak
melaleuca alternifolia
geranium
arnica
sea salt
Ash
Avens
Asiaticoside
acacia
Agave
Agrimony
Antirrhinum majus
Achyranthes
Anamu
Abrus
Alchornea
Alchemilla
Ajuga
Aquilegia formosa
Allantoin
Alkanet
Alsonia scholaris
Ampelopsis
Abuta
Alkanna
Bee Propolis
Bai Ji
Blackthorn
Balsam
Blackbrush
Butea monosperma
Barleria
Brazillian peppertree
Bee hive
Bloodroot
Benzoin
Bindweed
Banyan
Bletilla
Bee products
Bombax
Boerhavia diffusa
Calochortus
Comfrey
Centella triterpenes
Calendula
Calotropis gigantea
Colloidal Silver
Capillary Artemisia
Cinquefoil
Cattail
Cocoa Butter
Cymbidium goeringii
Cornflower
Cowherb
Centella asiatica
Celandine
Centipeda
Carrapichinho
Cedrus libani
Castile Soap
Cynodon dactylon
Cocklebur
Cynanchum
Casearia sylvestris
Didymocarpus
Dragon's Blood
Davilla rugosa
Epidermal Growth Factor
Erigeron
Elephant Vine
Erodium cicutarium
English Elm
Elephant's Head
Euphorbia
Flueggea suffruticosa
Fomes fomentarius
Ficin
Fibrinase
fibroblast growth factor
Fir
Genipap
Gnaphalium
Gambir
Genipa americana
Golden Shower Tree
Little ironweed
Oak
Polyvinyl alcohol