Ficin is a proteolytic enzyme extracted from the latex of the fig tree (Ficus carica). Its primary use in supporting or treating abrasions is based on its enzymatic debridement properties. Scientific literature indicates that proteolytic enzymes, including ficin, can facilitate the removal of necrotic tissue and promote wound healing by breaking down proteins and aiding in the cleaning of wounds such as abrasions. Ficin has been used in topical formulations for wound care, and some studies have shown that it can be effective in accelerating the debridement process and potentially improving the rate of healing when compared to standard care or placebo.

Clinical evidence supporting ficin's use is moderate: there are published studies, mostly from the mid-to-late 20th century, demonstrating its efficacy in wound debridement, especially in chronic wounds and ulcers. The mechanism is thought to be similar to that of other proteolytic enzymes like papain and bromelain. However, more recent large-scale randomized controlled trials are lacking, and ficin is less commonly used than other enzymes in modern clinical practice.

Overall, the scientific rationale for ficin's use in abrasions is supported by mechanistic studies and some clinical reports, but the quantity and quality of evidence are not robust by current standards. It is considered a scientifically plausible but not universally adopted therapy for wound care.