Zeaxanthin
Synopsis of zeaxanthin
Zeaxanthin is a carotenoid pigment belonging to the xanthophyll subclass, found naturally in many colorful fruits and vegetables, particularly those with yellow, orange, and green hues—such as corn, bell peppers, saffron, kale, and spinach. Alongside its close relative lutein, zeaxanthin is a major dietary antioxidant that plays a crucial role in maintaining eye health. It is one of the only dietary carotenoids that selectively accumulates in the human retina, particularly in the macula, where it helps form the macular pigment that protects against light-induced oxidative damage.
Zeaxanthin functions primarily as a free-radical scavenger, absorbing blue light and neutralizing reactive oxygen species in the retina. This action helps protect photoreceptor cells from oxidative stress, a key contributor to age-related macular degeneration (AMD) and other degenerative eye conditions. It is often included in supplements for visual health and is part of the AREDS2 (Age-Related Eye Disease Study 2) formula recommended for individuals at risk of AMD.
Beyond ocular support, zeaxanthin contributes to overall antioxidant defense in the skin and brain. Emerging studies suggest it may support cognitive function, skin resilience against UV damage, and vascular health, although these benefits are still under investigation.
Historical Use:
While zeaxanthin as a specific compound was not identified until the 19th century and isolated in the 20th century, the foods and herbs rich in this pigment have been used medicinally for millennia. Traditional diets across many cultures emphasized dark leafy greens, marigolds, and yellow-orange vegetables, which provided zeaxanthin and other carotenoids that supported vision and vitality—even if their precise chemical identities were unknown.
In Ayurvedic medicine, herbs like Tagetes erecta (Mexican marigold), which contains high levels of zeaxanthin and lutein, were used for improving eyesight, reducing eye strain, and supporting liver function—organs historically connected in traditional diagnostics. Similarly, Traditional Chinese Medicine recommended chrysanthemum tea (Ju Hua) for eye health, which also contains carotenoids.
The formal study of zeaxanthin began as part of the broader scientific effort to understand vitamins and micronutrients in the early 20th century. As the mechanisms of oxidative stress and light-induced retinal damage became clearer, the specific role of zeaxanthin emerged as central to eye protection. By the early 2000s, clinical studies confirmed its presence in the macula and its protective action against AMD, cementing its place in ophthalmology and preventive nutrition.
Zeaxanthin is used for these health conditions
Cataracts (Scientific)
Eye Problems (Scientific)
Eyes (spots before) (Scientific)
Eyesight (poor) (Scientific)
Macular Degeneration (Scientific)
