Synephrine
Other names for Synephrine
4 1-hydroxy 2 methyl
4-[1-hydroxy-2-(methylamino)ethyl] phenol
4-[1-hydroxy-2-(methylamino)ethyl]phenol
67.5mg synephrine alkaloids
isoproylnorsynephrine
naturally occuring synephrine
para-synephrine
para-synephrine alkaloids
para-synephrine hcl
providing 30 mg synephrine alkaloids
p-synephrine
p-synephrine content
sinefrina
synepherine
synephrine
synephrine 6% extract
synephrine alkaloids
synephrine caprylate
synephrine content
synephrine extract
synephrine extract 30%
synephrine group alkaloids
synephrine hcl
synephrine hcl 95%
synephrine hydrochloride
synephrines
syneprhine amines
Synopsis of Synephrine
History
Synephrine is a naturally occurring alkaloid predominantly found in the bitter orange (Citrus aurantium) plant. Its historical use in traditional medicine spans centuries, particularly in China and the Mediterranean region. In Traditional Chinese Medicine (TCM), extracts of bitter orange, known as "Zhi Shi," have been employed for their ability to support digestion, alleviate gastrointestinal discomfort, and promote energy. Healers often prescribed it as a remedy for indigestion, constipation, and mild nausea. Its mild stimulant properties were valued for enhancing alertness and uplifting mood without the intense side effects associated with other stimulants.
Historically, synephrine-containing remedies were also used in Mediterranean cultures to manage colds, support respiratory health, and encourage healthy circulation. Bitter orange peel teas and tinctures provided a gentle way to address fatigue and sluggishness, offering a natural boost for both body and mind.
Synephrine is often combined with other herbs to enhance its beneficial effects. In herbal formulas, it is paired with ingredients such as ginger, licorice root, or green tea to support metabolism, energy, and weight management. These combinations leverage synephrine’s thermogenic and appetite-suppressing properties, amplifying the overall wellness benefits. Many traditional blends use synephrine as a cornerstone for balancing herbal actions, making it a valuable addition to holistic approaches for vitality and health.
Overall, synephrine’s historical and contemporary uses highlight its important role in herbal medicine. Its gentle stimulatory effects, digestive support, and compatibility with other herbs make it a respected and versatile natural remedy with a positive legacy for promoting well-being.
Traditional and scientific validation
Synephrine is a naturally occurring alkaloid most commonly found in the bitter orange (Citrus aurantium) plant. Historically, extracts of bitter orange have been used in traditional Chinese medicine for various health purposes, including digestive issues and as a mild stimulant. With the restriction of ephedra in many countries, synephrine has gained popularity as an alternative ingredient in weight management and energy-boosting nutritional products.
Scientifically, synephrine is structurally similar to ephedrine, and it is believed to exert mild stimulatory effects, primarily by acting on adrenergic receptors. Several clinical studies have explored its potential benefits. For example, some randomized controlled trials have suggested that synephrine-containing supplements can modestly increase resting metabolic rate and energy expenditure, potentially supporting weight loss efforts when combined with diet and exercise. Additionally, preliminary research indicates that synephrine may enhance athletic performance by increasing alertness and perceived energy levels, though these effects tend to be less pronounced than those observed with stronger stimulants.
Despite its promising role in nutritional products, the evidence for synephrine’s efficacy and safety remains limited. Most studies are small-scale or involve multi-ingredient formulas, making it difficult to isolate synephrine’s specific contributions. Regulatory agencies generally consider synephrine to have a favorable safety profile when used at recommended dosages, but more extensive clinical research is needed to fully validate its long-term effects. Overall, synephrine represents a positive addition to the range of ingredients available for supporting metabolism and energy, with further studies likely to clarify its full potential in health and nutrition.
Synephrine is used for these health conditions
Athletic and Exercise Aids (Scientific)
Body Building (Scientific)
Energy (lack of) (Scientific)
Fat Metabolism (poor) (Scientific)
Weight Loss (Scientific)
Synephrine is used to support these body systems
Sympathetic Nervous System (Scientific)
