Sarivan

Other Names

Aeschynomene gangeticaAnshumatiBan GahatBidarikandaBrihatiChalaniDeergaangiDeergharpatraDesmodium gangeticumDeviDhruvaDirghamoolaDirghamulaDirghamuliDirghangriDirghapatrikaGanjotiGitanaramGuhaHedysarum gangeticumKolakannaruKolakuponnaKumudaMeibomia polygonodesMoovialMoovilaiMurelehonneNariyalavonaNischalaOrilaPivariPleurolobus gangeticusPulladiPullatiSaalvanSal Leaved DesmodiumSalapaniSalaparniSalavanSaloporniSalpanSalpaniSalparniSalpatriSalvanSalvanaSameravoSaripattraSarivanamSarivanchaSarvanSarvanukariniSaumyaSelopornoShal Leafed BushShalapaniShalaparniShalavanShaliparniShalparniShalpurniSharpaniShophaghniSophaghniSthiraSubhagaSudalaSumulaSuparniSupatrikaTanviTriparniVataghniVidarigandhaVrihiparnika

Synopsis

Sarivan (Desmodium gangeticum): An Encyclopedic Reference

1. Identity and Nomenclature

1.1 Botanical Name, Family, and Synonyms

Sarivan is the Hindi-language common name for the plant Desmodium gangeticum (L.) DC., a member of the family Fabaceae (Leguminosae), subfamily Faboideae. In India, the name "Sarivan" is used in botanical and Ayurvedic sources as a plant defined with Desmodium gangeticum. Its botanical synonyms include Meibomia polygonodes (Welw. ex Baker) Kuntze, among others.

The plant carries a wide array of Sanskrit and regional names reflecting its diverse usage across the Indian subcontinent. Desmodium gangeticum is commonly known as "Salpan" or "Salpani" in Hindi and "Shalparni" in Sanskrit, and is used in the Ayurveda, Siddha, and Unani systems of medicine either as a single drug or in combination with other drugs. Its Tamil and Malayalam name is "Pullati," and Sanskrit synonyms include Vidarigandha (fragrance like that of Vidari), Sthira (strengthening), and Sophaghni (reduces oedema), among others.

It is important to note a significant taxonomic ambiguity in the literature: the name "Sariva" (closely related to "Sarivan") is a broader Ayurvedic drug category applied to multiple plant species depending on regional practice. Controversies arose as practitioners in different parts of India used different plant species under the name Sariva. From available data, four species are being used as Sariva in different regions: Hemidesmus indicus is considered the botanical name of true Sariva, while Cryptolepis buchanani and Ichnocarpus are also collectively known as Sariva in Ayurveda, and in south India Decalepis hamiltonii is used as true Sariva. However, the specific term "Sarivan" in botanical and pharmacopeial references corresponds most precisely to Desmodium gangeticum, as confirmed by its inclusion in classical Ayurvedic formulations under that name.

1.2 Plant Description and Natural Source

Desmodium gangeticum (Shalparni) is a shrub with a woody stem, 2–4 feet in height. Branches are covered with soft hairs. Leaves are unifoliate, ovate, oblong, obtuse, and pubescent beneath and up to 15 cm in length. The lower surface of leaves is light green in colour. Flowers are purple or white in colour. Pods are thin, flat, and curved carrying 6–8 nodes and bear hair-like structures on them. Flowering and fruiting occur in the months of August and November.

D. gangeticum is a perennial non-climbing herb or shrub used in folklore medicine, and it widely shows a large number of medicinal properties, as well as contains divergent bioactive compounds. Many herbal formulations contain this medicinal plant, which is considered a master of medicinal plants in Ayurveda. Field investigations show that many tribes from the Western Ghats region of Kerala use this plant for the treatment of various ailments such as fever, typhoid fever, cough, diuretic uses, inflammations, asthma, and dysentery.

1.3 Common Preparations and Dosage Forms

Decoctions of root and leaf, root powder, and leaf juice of D. gangeticum are used as tonics, febrifuge, digestive, antiemetic, astringent, anti-asthmatic, antidiarrhoeal, and anti-inflammatory agents in traditional medicinal practices of India and its neighbouring countries. Traditionally, Ayurvedic practitioners use the root (moola) and the whole herb when fresh.

Sarivan appears in numerous classical Ayurvedic compound preparations in which it is one ingredient among many. The standard method of preparation of Chyawanprash, for example, specifies 50 g each of medicinal herbs including Gokshur, Sarivan, Barikateri, Kantakaari, and many others, suspended in 16 litres of potable water. The formula Dasamoolarishtam, which includes Sarivan, is used in postpartum care and as an anti-inflammatory.

In modern supplement contexts, Sarivani is increasingly incorporated into nutritional supplements and wellness teas, reflecting its enduring reputation as a rejuvenating and restorative botanical.

2. Traditional and Historical Use

2.1 Ayurveda

Sarivan holds a position of high esteem within Ayurvedic medicine, one of the world's oldest formalized healing systems. Traditional practice of Āyurveda in ancient India dates back to at least the first millennium BC. The illustration and description of this drug commences from the Vedic period itself, and its various therapeutic potential and uses are described in the Charaka Samhita, Sushruta Samhita, Ashtanga Hridaya, and Chikitsa Manjari.

Within the Ayurvedic classical framework, Sarivan is most prominently recognized as one of the ten herbs forming the celebrated Dashamoola (ten-root) group. Shalparni (Desmodium gangeticum) is among the most important herbs in Ayurveda, forming one of the herbs of Dashmoola — the group of 10 herbs. As a component of the Dashmula group, it is reported to have marked analgesic and anti-inflammatory properties, and it is also used as an important constituent in many Rasayana formulations. The Dashamoola group is further subdivided into Brihat Panchamoola (five larger roots) and Laghu Panchamoola (five smaller roots); Shalparni is one of the Laghupanchamoola ingredients, and Desmodium gangeticum DC. is an accepted source of Shalparni as per the Ayurvedic Pharmacopoeia of India (API).

In the Ayurvedic system of medicine, Desmodium gangeticum is used as a tonic, febrifuge, digestive, anticatarrhal, and antiemetic, and in inflammatory conditions of the chest and in various other inflammatory conditions. This herb has anthelmintic, anti-catarrhal, carminative, diuretic, expectorant, febrifuge, nervine tonic, anti-diarrheal, and stomachic properties as recorded in traditional practice.

Classical texts categorize Sarivan within several specific therapeutic groups. In the Charaka Samhita, it is listed in the Jvarahara group (herbs used in treating fever), the Daha Prashamana group (herbs that relieve burning sensation), the Pureesha Sangahaniya group (herbs that improve bulk of feces), the Stanya shodhana group (herbs that cleanse and detoxify breast milk), and the Madhura skandha (sweet taste) category.

Ayurvedic tradition also employs Sarivan in the Snehopaga context — herbs facilitating oleation therapy. The fourth chapter of Charaka Samhita Sutra Sthana details fifty Mahakashaya used in various diseases, and Snehopaga is a group of drugs that help promote unctuousness or aid the oleation therapy. In circulatory applications, it is indicated in edema and acts as a cardiac tonic; the preparation Ksheerapaka of Salaparni is indicated in Hridsula (cardiac pain). For the respiratory system, it is used to expel vitiated Kapha dosha and is indicated in emaciation and tuberculosis.

2.2 Siddha and Unani Systems

Beyond Ayurveda, Sarivan is incorporated in two other major traditional South Asian medical systems. Desmodium gangeticum is used in Ayurveda, Siddha, and Unani systems of medicine either as a single drug or in combination with other drugs. In Unani medicine, the preparation "Arq dashmul" contains this species' root extract and is used against leucorrhoea and for pains due to cold.

2.3 Use in Chyawanprash

Sarivan is one of the constituent herbs of Chyawanprash, perhaps the most celebrated classical Ayurvedic compound. Chyawanprash (CP) is an Ayurvedic health supplement made up of a super-concentrated blend of nutrient-rich herbs and minerals, meant to restore drained reserves of life force (ojas) and to preserve strength, stamina, and vitality, while stalling the course of aging. Sarivan, alongside Draaksha, Haritaki, honey, Bhumyamalaki, Kachur, Pushkarmul, Musta, and Kaknasa, is among the ingredients that help to improve digestion and metabolism.

2.4 Traditional Preparations and Application Methods

Traditional applications of Sarivan involved a variety of preparation forms adapted to the target condition. In skin diseases (Kushta), the combination of Amalaki and Sariva is used for drinking, bathing, and external application to cure skin diseases. In itching (Kandu), bathing in a decoction of root of Sariva was used to cure itching. In thirst (Trishna), crushed root pieces are added with water and boiled. The roots have been used as an expectorant and in snake bite and scorpion sting in traditional practice.

In classical combination therapy, in classical Ayurvedic formulations, Sarivani is commonly paired with Manjistha (Rubia cordifolia) for enhanced blood purification, or with Guduchi (Tinospora cordifolia) to heighten its immune-boosting effects.

3. Key Constituents and Active Compounds

3.1 Phytochemical Profile

Scientific phytochemical investigations of Desmodium gangeticum have revealed a complex and diverse array of bioactive compounds. Desmodium gangeticum is enriched in alkaloids, terpenoids, steroids, flavonoids, phenylpropanoids, pterocarpans, volatile oil, coumarins, phenol, isoflavonoid, glycoside, pterocarpenoid, and saponin.

Phytochemical profiling showed that the ethanolic extract of the aerial part contains glycoside, amino acid, phenols, alkaloids, flavonoids, and coumarins, while the ethanolic root extract of the plant revealed the presence of glycoside, amino acid, phenols, alkaloids, flavonoids, coumarins, and triterpenoids. FTIR analysis indicated that the plant extracts are mainly rich in phenolic derivatives. The compounds gangetin (1a), gangetinin (1b), desmocarpin (1c), and desmodin (1d) belong to the pterocarpan class of phenolic derivatives reported from the species D. gangeticum. The pterocarpans constitute the second largest group of natural isoflavonoids and show many biological properties.

Phytochemical research on Desmodium gangeticum has led to the isolation of alkaloids, pterocarpans, phospholipids, sterols, flavones, and flavonoid glycosides. Additional identified constituents include: gangeticoside, leonuriside A, tortoside A, dehydrosoyasaponin, gangetin, gangetinin, desmocarpin, and desmodin.

3.2 Key Bioactive Compounds and Their Properties

Gangetin and Gangetinin (Pterocarpans/Alkaloids): The alkaloids gangetin and gangetinin show antispasmodic activity, likely contributing to bronchial smooth muscle relaxation. Gangetin, which belongs to the pterocarpans, is reported to have anti-inflammatory and analgesic effects. Gangetin has also been studied for its antioxidant and antileishmanial activities as a pterocarpene glycoside.
Desmodin: Desmodin belongs to the class of pterocarpans and is reported to have antifungal and antibacterial activities.
Flavonoids (Quercetin, Kaempferol, Vitexin): Key compounds isolated include flavonoids like quercetin and kaempferol, alkaloids such as gangetin, and the unique triterpenoid desmodin. As literature demonstrates, flavonoids and alkaloids are perhaps responsible for most of the activities shown by the plants of this genus.
Phenolic Derivatives: FTIR spectroscopy showed that D. gangeticum extracts are mainly rich in phenolic derivatives. These are believed to underlie much of the antioxidant activity observed in laboratory studies.
Alkaloids (Hordenine, Hypaphorine, Tyramine): Leaf content includes alkaloids like hypaphorine, β-phenylethylamine, and tyramine, as well as flavonoids. The diverse phytochemical profile, particularly its alkaloid components, confers anti-inflammatory, analgesic, and antioxidant properties.
Minerals: Due to the presence of alkaloids, vitamins, oils, and minerals like calcium, phosphorous, and magnesium, Desmodium gangeticum was used by Ayurvedic and Unani specialists to treat a range of conditions.

4. Pharmacological Research and Mechanisms of Action

4.1 Overview

Crude extracts, fractions, and isolated components of Desmodium gangeticum showed a wide spectrum of in vitro and in vivo pharmacological activities, including antileishmanial, immunomodulatory, antiasthmatic, smooth muscle relaxant, anti-inflammatory, anti-ulcer, cardio-protective, antidiabetic, antiamnesic, antiviral, antioxidant, and hepatoprotective activities. It must be emphasized throughout this section that the overwhelming body of this evidence is preclinical — derived from in vitro cell-based assays or animal model studies — and that robust, controlled human clinical trials specifically on Sarivan as a standalone agent are absent from the peer-reviewed literature.

4.2 Anti-inflammatory and Analgesic Activity

Desmodium gangeticum has been demonstrated to possess antioxidant, anti-nociceptive, and anti-inflammatory properties, as documented in studies by Govindarajan et al. (2007) and Rathi et al. (2004). The anti-inflammatory and anti-nociceptive activity of the water decoction of D. gangeticum was evaluated in animal models (published in the Journal of Ethnopharmacology, 2004), contributing early preclinical evidence for use in pain and inflammatory conditions. Gangetin, the pterocarpan alkaloid, is specifically reported to have anti-inflammatory and analgesic effects. These activities align with the plant's longstanding Ayurvedic application in inflammatory chest conditions and joint disorders, though no controlled human clinical trials directly verify this mechanism in humans.

4.3 Antioxidant Activity

Desmodium gangeticum is a herbal species widely used in the indigenous system of medicine and is reported to contain flavone and isoflavonoid glycosides. A study examining antioxidant activities (PubMed PMID 14519948) was conducted using rat brain homogenate by the thiobarbituric acid-reactive substances (TBARS) method. Ethanolic extract of Desmodium gangeticum aerial part confirmed the presence of antioxidant activity by the DPPH method. These findings are in vitro and animal-model based; human data are lacking.

4.4 Cardioprotective Activity

Desmodium gangeticum possesses the ability to scavenge the free radicals generated during ischaemia and ischaemia-reperfusion, thereby preserving the mitochondrial respiratory enzymes that eventually lead to cardio-protection. A study by Kurian et al. (2008, published in Journal of Pharmacy and Pharmacology) demonstrated that methanol extract of Desmodium gangeticum roots preserves mitochondrial respiratory enzymes, protecting rat heart against oxidative stress induced by reperfusion injury. This research is confined to animal (rat) models; no human cardioprotection trials have been reported.

4.5 Antidiabetic Activity

A study by Govindarajan et al. (2007, Planta Medica) examined the effect of Desmodium gangeticum extract on blood glucose in rats and on insulin secretion in vitro (PubMed PMID 17431824). It is reported that D. gangeticum extracts showed potent antioxidant, antibacterial, hypoglycaemic, analgesic, hepatoprotective, and antiinflammatory activities. All available antidiabetic evidence for D. gangeticum as a standalone agent remains at the preclinical (animal and in vitro) level.

4.6 Hepatoprotective Activity

Some preclinical research — primarily in vitro and animal models — suggests that extracts of Tephrosia purpurea may exhibit hepatoprotective effects, possibly by reducing oxidative stress and inflammation in liver tissue. For D. gangeticum specifically, hepatoprotective properties have been demonstrated in preclinical studies, as noted alongside other pharmacological activities documented in the scientific literature. A study by Dharmani et al. (2005) evaluated anti-ulcer effects, also cited within the same preclinical literature corpus. Clinical hepatoprotection evidence in humans is not available.

4.7 Antileishmanial Activity

Desmodium gangeticum has potential prophylactic and therapeutic efficacy against Leishmania infection, as established in preclinical models. This activity has been attributed to the pterocarpan compound gangetin. Gangetin, a pterocarpene glycoside, has been studied for its antileishmanial activities alongside antioxidant properties. No human clinical trials for leishmaniasis treatment using D. gangeticum extracts have been reported.

4.8 Immunomodulatory Activity

Numerous therapeutic activities have been documented in the scientific literature, including immunomodulatory activity, based on in vitro and animal experiments. The immunomodulatory action is consistent with the herb's traditional role as a Rasayana (rejuvenative tonic). Human clinical immunology data specific to the herb as a standalone agent are not present in the peer-reviewed literature reviewed here.

4.9 Antiamnesic / Cognitive Activity

Sariva is a widely used herbal drug in the management of cognitive disorders from the times of Acharya Charaka till today. Preclinical evidence from animal model studies indicates antiamnesic properties. Antiamnesic activity was among the wide spectrum of in vitro and in vivo pharmacological activities demonstrated for D. gangeticum extracts and isolated components. No controlled human cognitive trials specific to Sarivan have been identified.

4.10 Smooth Muscle Relaxant and Antiasthmatic Activity

The dried roots of the plant demonstrate anti-asthmatic properties across chloroform, water, and ethanolic extracts. The alkaloids gangetin and gangetinin show antispasmodic activity, likely contributing to bronchial smooth muscle relaxation. Animal model studies and in vitro assays form the evidence base; human respiratory trials have not been specifically conducted on the isolated plant.

5. Body Systems and Health Areas Associated with Sarivan

5.1 Respiratory System

Sarivan is prominently associated with respiratory health in both traditional and preclinical scientific contexts. Desmodium gangeticum is a traditional Ayurvedic plant used for centuries as an anti-catarrahal, expectorant, bronchodilator, and anti-inflammatory agent. Shalparni is considered an effective medicinal plant when it comes to controlling bronchitis. As a component of Dasamoola formulations, it is indicated classically for chest inflammations.

5.2 Cardiovascular System

In circulatory applications, Sarivan is indicated in edema and acts as a cardiac tonic in Ayurvedic tradition. Preclinical data on ischaemia-reperfusion injury in rat models support cardioprotective claims at the mechanistic level, but human cardiovascular efficacy data are absent. Despite a large number of traditional therapeutic uses, D. gangeticum was evaluated for limited therapeutic efficacy through clinical trials, and evidence suggested it may have therapeutic benefits on bronchitis, gout, and hypertension.

5.3 Digestive System

In digestive applications, Sarivan is described as carminative, unctuous, and absorbent, with anthelmintic properties, and is indicated in vomiting, diarrhea, helminthiasis, and haemorrhoids. Preclinical anti-ulcer activity has been documented in animal studies (Dharmani et al., 2005).

5.4 Nervous System

Sarivan is traditionally attributed with the ability to strengthen the nervous system and pacify vata dosha. Preclinical antiamnesic data in animal models form the basis for its association with cognitive health. Human clinical data are not available for this indication.

5.5 Hepatic System

In Ayurveda, Sarivan is considered to have hepatoprotective properties and is included in several classical formulations aimed at promoting liver function and addressing symptoms associated with liver inflammation. Scientific studies on its efficacy in treating hepatitis are limited.

5.6 Musculoskeletal System

As a member of the Dashmula group, Shalparni exhibits considerable analgesic and anti-inflammatory properties, which underpin its classical use in joint and musculoskeletal disorders attributed to Vata imbalance. Anti-nociceptive and anti-arthritic activity has been demonstrated in preclinical animal studies.

5.7 Immune System

As a component of Chyawanprash, Sarivan is part of an ancient synergistic blend traditionally used to improve respiratory health, strengthen the immune system, prevent recurrence of infections, and known for its anti-inflammatory and antioxidant properties. Its direct, isolated immunomodulatory contribution in human subjects has not been clinically quantified.

6. Scientific Evidence by Area of Use — Strength Assessment

6.1 Anti-inflammatory / Analgesic — Preclinical Evidence Only

Available evidence: In vitro cell assays and animal model studies (e.g., Rathi et al., 2004, Journal of Ethnopharmacology; Govindarajan et al., 2007, Planta Medica). Scientific experiments carried out in vitro as well as preclinical animal experimentations showed that the plant and its bioactive chemicals exhibit various therapeutic activities. Evidence strength: Preliminary (preclinical only). No randomized controlled trials (RCTs) in humans.

6.2 Antidiabetic — Preclinical Evidence Only

Preclinical studies in rat models (Govindarajan et al., 2007) demonstrated blood glucose-lowering effects and stimulation of insulin secretion in vitro. Evidence strength: Preliminary (preclinical only). No human trials.

6.3 Cardioprotection — Preclinical Evidence Only

Rat model studies documenting preservation of mitochondrial respiratory enzyme function in ischaemia-reperfusion contexts (Kurian et al., 2008, Journal of Pharmacy and Pharmacology). Evidence strength: Preliminary (animal model only).

6.4 Antileishmanial — Preclinical Evidence Only

In vitro and animal model data using gangetin and plant extracts. Evidence strength: Preliminary (in vitro and animal model).

6.5 Hepatoprotective — Preliminary Preclinical Evidence

The use of Sarivan for hepatitis is primarily rooted in traditional practice rather than robust scientific evidence. Preliminary preclinical research suggests oxidative stress reduction in liver tissue models. Evidence strength: Very preliminary; no human data.

6.6 Cognitive / Antiamnesic — Preclinical Evidence Only

Animal model data for antiamnesic activity. The direct scientific evidence supporting Sarivan's efficacy for cognitive or sleep disorders is limited. While Desmodium gangeticum has been investigated for a range of pharmacological effects — such as anti-inflammatory, antioxidant, and hepatoprotective properties — there is a lack of robust modern clinical trials or preclinical studies specifically evaluating certain traditional indications. Evidence strength: Preliminary (animal model only).

6.7 Respiratory Health (Antiasthmatic / Bronchodilatory) — Preclinical + Traditional

Extract-based bronchodilatory and smooth-muscle relaxant effects have been documented in preclinical studies across multiple extract types (chloroform, water, ethanol). Desmodium adscendens, a closely related species, is useful against chronic bronchitis and asthma, and the genus as a whole carries this traditional attribution. Evidence strength for D. gangeticum specifically: Traditional use well-documented; preclinical support exists; human clinical trials lacking.

6.8 Overall Evidence Summary

Despite these promising findings, robust clinical trials in humans remain limited. Much of the current evidence is based on traditional use and preclinical data, and more comprehensive, controlled studies are needed to fully validate the health claims associated with Sarivan. Despite a large number of traditional therapeutic uses, D. gangeticum was evaluated for limited therapeutic efficacy through clinical trials, and evidence suggested it may have therapeutic benefits on bronchitis, gout, and hypertension — though these clinical observations have not been confirmed through large, randomized controlled trials.

7. Dosage Forms Reported in Sources

The following dosage references are drawn directly from traditional and pharmacopeial contexts; they should be interpreted as traditional recommendations rather than clinically validated therapeutic doses:

Root powder (churna): Root powder (churna) of 1–3 g, mixed with warm water, twice daily after meals, is referenced as a traditional preparation preferred for digestive and joint issues.
As a component in compound formulas: In the preparation of Chyawanprash, 50 g of each medicinal herb including Sarivan is used as part of the standard formula, suspended in 16 litres of potable water prior to decoction.
Root decoction: Decoctions of root are prepared in traditional practice, with the quantity determined by classical Ayurvedic texts and the treating vaidya (Ayurvedic practitioner). No standardized mg/kg dose has been established through human clinical trials for any indication.

Studies reported that D. gangeticum or its formulations are safe when used in appropriate therapeutic dosage, though what constitutes an "appropriate" dose has not been formally established in peer-reviewed clinical trial literature.

8. Adulteration and Botanical Identity Concerns

A significant practical concern for consumers and formulators is the prevalence of adulteration and botanical misidentification. Due to the high medicinal properties of this species and increasing market demand, adulteration of genuine herbs with low-grade ones has increased significantly. Research has provided validated genomic (genome skimming and DNA probes) and metabolomic (NMR chemical fingerprints) biotechnology solutions to prevent adulteration on both raw materials and finished products. This also represents the first use of Oxford Nanopore on herbal products, enabling genome skimming as a tool for quality assurance within the supply chain of botanical ingredients.

Desmodium laxiflorum DC. is commonly used instead of D. gangeticum in the Saurashtra region. Both species show the same Rasa (taste) and Anurasa and almost the same morphological and microscopical characters, suggesting D. laxiflorum may be considered a substitute for D. gangeticum on the basis of pharmacognostical comparison, though this substitution has not been validated through comparative clinical trials.

9. Safety Considerations

Formal toxicological data on Desmodium gangeticum from controlled human studies are very limited. The safety information available derives primarily from traditional use records, preclinical studies, and general regulatory context.

Preclinical safety: Studies reported that D. gangeticum or its formulations are safe when used in appropriate therapeutic dosage. This assessment is based on preclinical studies, not systematic human safety trials.
Potential for toxicity at excess doses: References in Ayurvedic practice note that overdosage of Shalparni may be poisonous or cause serious toxic side effects, as noted in citations to the Ayurvedic Pharmacopoeia of India, though the specific toxic dose has not been established in human studies.
Interactions with other medicines: Some Ayurvedic herbs can interact with modern medicines, and practitioners advise seeking guidance when this product is taken alongside other Western (allopathic/modern) medicines. No specific pharmacokinetic drug-interaction studies for D. gangeticum in humans have been identified in the peer-reviewed literature.
Regulatory status: Rules for manufacturing and distributing dietary supplements are less strict than those for prescription or over-the-counter drugs. Although the U.S. Food and Drug Administration requires that companies submit safety data about any new ingredient not sold in the United States in a dietary supplement before 1994, the FDA is not authorized to review dietary supplements for safety and effectiveness before they are marketed.
Supply chain quality: Due to increasing demand for herbal medicine, adulteration of genuine herbs with low-grade ones has increased significantly, which will affect the therapeutic efficiency of the drug.
Populations not studied: No clinical safety data are available specifically for pregnant women, nursing mothers, children, or individuals with chronic diseases with respect to Sarivan as a standalone supplement.

References

Health Conditions

Health conditions that Sarivan may help support.

No conditions available.

Body Systems

Body systems that Sarivan may help support.

No body systems available.