Pyrroloquinoline Quinone
Other names for Pyrroloquinoline Quinone
biopqq
biopqq pyrroloquinoline quinone disodium salt
biopqq(r) pyrroloquinoline quinone disodium salt
bio-pqq(tm)
lifepqq
mgcpqq
microactive pqq
micropqq
mitop2q
pqq
pqq (biopqq(tm)) pyrroloquinoline quinone disodium salt
pqq disodium salt
pqq (pyrroloquinoline quinone) disodium salt
providing pyrroloquinoline quinone
pure pqq
pureqq
pureqq pyrroloquinoline quinone
pyrroloquinoline disodium salt
pyrroloquinoline quinone
pyrroloquinoline quinone disodium
pyrroloquinoline quinone disodium salt
pyrroloquinoline quinone disodium salt complex
pyrroloquinoline quinone disodium salt trihydrate
pyrroloquinoline quinone (pqq) disodium salt
Synopsis of Pyrroloquinoline Quinone
History
Pyrroloquinoline Quinone (PQQ) is a redox cofactor and antioxidant that has garnered significant interest in recent years for its potential health benefits. Historically, while PQQ itself was only formally identified in the late 20th century, the compounds and foods rich in PQQ—such as fermented soybeans (natto), green tea, and certain medicinal mushrooms—have long been used in traditional medicine for their rejuvenating and vitality-enhancing properties. Ancient remedies in East Asia, for example, often combined these foods for their reported ability to boost energy, promote longevity, and enhance cognitive clarity.
PQQ’s medicinal value lies primarily in its potent antioxidant capacity and its ability to support mitochondrial health. In traditional herbal medicine, ingredients now known to contain PQQ were commonly included in tonics aimed at combating fatigue, increasing stamina, and supporting brain function. Modern research has substantiated many of these uses, showing that PQQ can stimulate the growth of new mitochondria (mitochondrial biogenesis), which may underpin many of the energizing effects observed in ancient remedies.
In contemporary herbal combinations, PQQ is often paired with other synergistic nutrients such as Coenzyme Q10, B vitamins, and herbal extracts like ginseng and ashwagandha. These combinations leverage PQQ’s antioxidant and neuroprotective effects, making them popular choices for supporting cognitive health, memory, and overall vitality. The positive contributions of PQQ, both historically and in modern use, highlight its value as a natural compound that bridges traditional wisdom with current nutritional science, helping to enhance health and well-being in a safe and effective manner.
Traditional and scientific validation
Pyrroloquinoline Quinone (PQQ) is a redox cofactor first identified in bacteria in the late 1970s. Initially recognized for its role in microbial enzymatic reactions, PQQ has more recently garnered attention as a dietary supplement ingredient due to its potential health benefits. Animal studies have suggested that PQQ may play a role in mitochondrial biogenesis, neuroprotection, and antioxidant defense. These properties have led to increased interest in its possible contributions to human health, particularly in areas related to cognitive function and energy metabolism.
Clinical research on PQQ in humans remains limited but promising. Several small-scale clinical trials have indicated that PQQ supplementation may improve markers of cognitive performance, such as attention and memory, particularly in older adults. Other studies have suggested that PQQ may support mitochondrial function and reduce markers of oxidative stress. For example, a double-blind, placebo-controlled study published in 2009 found improvements in fatigue and sleep quality among participants taking PQQ supplements.
Despite these encouraging findings, it is important to note that the body of scientific evidence for PQQ’s benefits in humans is still emerging. Most studies to date have been short-term and involved relatively small sample sizes. As such, more rigorous and long-term clinical trials are needed to confirm its efficacy and safety. Nonetheless, PQQ remains a promising ingredient in nutritional products, valued for its antioxidant properties and its potential role in supporting cognitive and cellular health.
Pyrroloquinoline Quinone is used for these health conditions
Aging (prevention) (Scientific)
Alzheimer's Disease (Scientific)
Athletic and Exercise Aids (Scientific)
Cardiovascular Disease (Scientific)
Depression (Scientific)
Diabetes (Scientific)
Energy (lack of) (Scientific)
Fatigue (Scientific)
Free Radical Damage (Scientific)
Inflammation (Scientific)
Memory and Brain Function (Scientific)
Metabolic Syndrome (Scientific)
Nerve Damage (Scientific)
Parkinson's Disease (Scientific)
Stress (Scientific)
Pyrroloquinoline Quinone is used to support these body systems
Brain (Scientific)
Heart (Scientific)
Immune System (Scientific)
Mitochondria (Scientific)
Nerves (Scientific)