L-Alanyl-Glutamine
Other names for L-Alanyl-Glutamine
alanyl-glutamine
alanylglutamine
alanyl-l-glutamine dipeptide
l-alanyl glutamine
l-alanyl-glutamine
l-alanyl l-glutamine
l-alanyl-l-glutamine
l-alanyl-lglutamine
l-alanyl-l-glutamine dipeptide
l-sustamine
recovamine
sustamine
sustamine alanyl-glutamine
sustamine l-alanyl-l-glutamine
sustamine(r)
sustamine(tm)
sustamine(tm) alanyl-glutamine
sustamine(tm) l-alanyl-l-glutamine
sustamine(tm) l-alanyl l-glutamine dipeptide
t.a.g.
trans-alanyl-glutamine
Synopsis of L-Alanyl-Glutamine
History
L-Alanyl-Glutamine is a dipeptide composed of the amino acids L-alanine and L-glutamine, developed to enhance the stability and absorption of glutamine. While its synthesis and application are relatively modern, its key component, glutamine, has been recognized for its health benefits for decades. Historically, glutamine has been utilized in clinical nutrition to support gut health, immune function, and muscle recovery, especially in patients experiencing trauma, surgery, or critical illness. Early research in the late 20th century highlighted glutamine’s role in maintaining intestinal integrity and reducing infection risk, making it a valuable ingredient in enteral and parenteral nutrition.
The creation of L-Alanyl-Glutamine addressed glutamine’s instability in aqueous solutions, providing a more effective means of delivery. This innovation has been particularly beneficial in medical nutrition therapy, where it helps promote tissue repair, reduce muscle wasting, and enhance recovery in hospitalized patients. Its positive impact on gut mucosa and immune response has been well documented, supporting its continued inclusion in nutritional supplements and medical foods.
In the context of herbal combinations, L-Alanyl-Glutamine can complement traditional remedies that aim to support digestive and immune health. When paired with herbal extracts such as ginger, licorice, or slippery elm, it may work synergistically to soothe the gastrointestinal tract and aid in nutrient absorption. These combinations harness the strengths of both modern amino acid science and traditional herbal wisdom, contributing to holistic wellness. Overall, L-Alanyl-Glutamine stands as a testament to the advancement of nutritional science, providing tangible benefits in both clinical and wellness applications.
Traditional and scientific validation
L-Alanyl-Glutamine is a dipeptide composed of the amino acids L-alanine and L-glutamine, developed to enhance glutamine stability and absorption in nutritional formulations. Historically, glutamine has been recognized for its pivotal role in protein synthesis, gut health, and immune function. However, free glutamine is unstable in solution, especially under heat or acidic conditions common in enteral and parenteral feeds. The synthesis of L-Alanyl-Glutamine addressed these challenges, offering a stable, water-soluble alternative that efficiently delivers glutamine to the body.
Scientific research supports the use of L-Alanyl-Glutamine in clinical nutrition. Several studies have demonstrated that this dipeptide is well-tolerated and effectively increases plasma glutamine levels, even in critically ill patients. Clinical trials have investigated its application in parenteral nutrition for patients undergoing surgery, trauma, or intensive care, with some reports indicating improved nitrogen balance, reduced infection rates, and faster recovery times. In athletes, supplementation has been associated with better hydration and reduced muscle soreness, though findings are still preliminary.
Despite these promising outcomes, the full spectrum of L-Alanyl-Glutamine’s benefits requires further validation through larger, long-term studies. Nonetheless, its enhanced stability and bioavailability make it a valuable ingredient in nutritional products for patients with increased metabolic demands or compromised gut function. As research continues, L-Alanyl-Glutamine stands out as a scientifically grounded and innovative solution for supporting nutrition and recovery in various populations.
L-Alanyl-Glutamine is used for these health conditions
Athletic and Exercise Aids (Scientific)
Body Building (Scientific)
Dehydration (Scientific)
Diarrhea (Scientific)
Endurance (lack of) (Scientific)
Exercise (Scientific)
Fatigue (Scientific)
Surgery (healing from) (Scientific)
L-Alanyl-Glutamine is used to support these body systems
Digestive System (Scientific)
Gastrointestinal Tract (Scientific)
Immune System (Scientific)
Intestinal System (Scientific)
Muscles (Scientific)
Small Intestines (Scientific)
