Glycine
Other names for Glycine
glycine
glycine, micronized
glycine, powder
l-glycine
l-glycine hydrochloride
l-glycine, micronized
l-glycine, powder
l-glycine usp
glycine
Glycine propionyl-l-carnitine
Glycine-alanyl-l-histidine
Glycine-alanyl-l-isoleucine
Glycine-alanyl-l-leucine
Glycine-alanyl-l-lysine
Glycine-alanyl-l-methionine
Glycine-alanyl-l-phenylalanine
Glycine-alanyl-l-threonine
Glycine-alanyl-l-tryptophan
Glycine-alanyl-l-valine
Glycine-alanyl-lysine-l-citrulline
Glycine-alanyl-lysine-l-glutamine
Glycine-Arginine alpha-ketoisocaproate
Glycitein
Synopsis of Glycine
History
Glycine, the simplest amino acid, has a storied history in medicinal traditions for its beneficial effects on health and wellness. Historically, glycine-rich foods and broths—such as those derived from animal bones and skin—were consumed in ancient cultures for their restorative properties, especially in convalescence and digestive complaints. Early records from traditional Chinese and Greek medicine reference the use of gelatin-rich preparations, inherently high in glycine, as soothing agents for the stomach and as promoters of overall vitality.
Glycine’s reputation as a remedy has grown with scientific understanding. It has long been utilized as a mild sweetener and stabilizer in medicinal syrups and tonics, enhancing both the flavor and bioavailability of herbal extracts. Its calming effect on the nervous system led to its inclusion in remedies for sleep disturbances and anxiety, supporting relaxation and mental clarity. In addition, glycine’s role in the synthesis of collagen made it a popular ingredient for skin health and wound healing in traditional ointments and salves.
In herbal combinations, glycine serves as a synergistic partner, amplifying the effects of botanicals such as valerian root, passionflower, and chamomile. By facilitating neurotransmitter balance and reducing inflammation, it complements these herbs’ calming and restorative properties. Modern nutritional products continue this tradition, blending glycine with herbs and nutrients to support mood, cognitive function, and metabolic health. Its versatility and safety profile underscore glycine’s enduring value in both traditional and contemporary wellness practices, making it a cherished ingredient in holistic health formulations.
Traditional and scientific validation
Glycine, the simplest amino acid, has been recognized for decades as a vital building block in human nutrition and physiology. Historically, glycine was first isolated from gelatin in the early 19th century and its role in protein synthesis and metabolic processes was established soon after. Its inclusion in nutritional products is based on its essential contributions to collagen formation, neurotransmission, and detoxification pathways.
Scientific validation for glycine’s use in nutrition is supported by a range of laboratory and clinical studies. Research suggests glycine supplementation may promote better sleep quality, reduce symptoms of metabolic syndrome, and support joint and skin health due to its role in collagen synthesis. For example, small-scale human trials have shown that nightly glycine intake can improve sleep efficiency and decrease fatigue. Other studies indicate potential benefits for glucose regulation and anti-inflammatory effects, though these findings are preliminary and require larger, long-term investigations.
Glycine is also recognized as a conditionally essential amino acid in times of metabolic stress, emphasizing its importance in recovery and overall wellness. While more rigorous clinical trials are needed to fully substantiate all claimed health benefits, current evidence underscores glycine’s safety and utility as a nutritional ingredient. Its well-tolerated profile and fundamental physiological functions make it a valuable addition to nutritional products aimed at supporting general health and well-being.
Glycine is used for these health conditions
Anxiety (Scientific)
Cardiovascular Disease (Scientific)
Concentration (poor) (Scientific)
Depression (Scientific)
Diabetes (Scientific)
Hypertension (Scientific)
Inflammation (Scientific)
Insomnia (Scientific)
Liver Detoxification (Scientific)
Memory and Brain Function (Scientific)
Stress (Scientific)
Ulcers (Scientific)
Wounds and Sores (Scientific)
Glycine is used to support these body systems
Blood (Scientific)
Brain (Scientific)
Digestive System (Scientific)
Gastrointestinal Tract (Scientific)
Joints (Scientific)
Liver (Scientific)
Muscles (Scientific)
Nerves (Scientific)
Skin (Scientific)
Structural System (Scientific)
