Dioscorea (Dioscorea villosa)

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Other names for dioscorea

Wild Yam
Dioscorea villosa
Mexican Yam Extract
Dioscorea collettii
Dioscorea collettii var. hypoglauca
Dioscorea collettii vs. hypoglauca
Dioscorea hondurensis
Dioscorea nipponica
Dioscorea oppositifolia

Synopsis of dioscorea

Dioscorea refers to a large genus of plants commonly known as wild yam, with Dioscorea villosa being the most medicinally recognized species. Native to North America, this twining vine with thick, tuberous roots has long been valued for its use in supporting women’s reproductive health, hormone balance, and inflammation management. While Dioscorea roots contain a compound called diosgenin, a plant-based steroidal saponin, it does not convert to hormones in the human body—but it has been used as a raw material in the laboratory synthesis of progesterone, DHEA, and other corticosteroids.

Medicinally, Dioscorea villosa (wild yam) is used to:

  • Support menstrual and menopausal balance, especially for cramps, hot flashes, and mood swings
  • Act as a uterine antispasmodic, helping ease dysmenorrhea (painful periods) and ovarian discomfort
  • Relieve digestive cramping and intestinal colic
  • Reduce musculoskeletal tension and joint pain, particularly in herbal formulas for rheumatism or fibromyalgia
  • Act as a gentle tonic for the nervous system, especially when stress affects the reproductive organs

Dioscorea is commonly prepared as tincture, capsules, dried root, or topical creams, though many topical "wild yam creams" claiming to affect hormone levels are controversial and not well-supported by clinical evidence.

Historical Use
Dioscorea villosa was traditionally used by Native American tribes, including the Cherokee and Delaware, to treat menstrual cramps, labor pains, and digestive upset. The root was often decocted into a tea or poultice, and also used as a remedy for arthritic pain, neuralgia, and snakebite.

In 19th-century Western herbalism, Dioscorea became widely known as “colic root”, a remedy for gripping gastrointestinal spasms, gallbladder pain, and menstrual distress. It was embraced by the Eclectic physicians for its antispasmodic and soothing qualities, and prescribed in cases of bilious colic, dysmenorrhea, and pelvic congestion.

The connection between wild yam and hormone health gained popularity in the mid-20th century, when researchers discovered that diosgenin could be chemically converted into progesterone in the lab. This led to widespread marketing of wild yam as a “natural alternative to hormone therapy,” though this conversion does not occur naturally in the body—it requires industrial processing.

In modern herbalism, wild yam remains a staple for:

  • Menstrual and menopausal support, often in combination with chaste tree, black cohosh, and dong quai
  • Muscle and digestive relaxation, especially when stress or hormonal imbalance is involved
  • Formulas for pelvic congestion, fibroids, and hormonal acne

Today, Dioscorea is best understood as a soothing, antispasmodic herb with mild endocrine support effects, valued in women's health protocols but not a direct source of bioidentical hormones.

Dioscorea is used for these health conditions

Abdominal Pain (Traditional)
Amenorrhea (Traditional)
Appetite (deficient) (Traditional)
Arthritis (Traditional)
Asthma (Traditional)
Backache (Traditional)
Breast Lumps (Traditional)
Breasts (enhance size) (Traditional)
Bronchitis (Traditional)
Burns and Scalds (Traditional)
Cancer (natural therapy for) (Traditional)
Cancer Treatment (reducing side effects) (Traditional)
Cholesterol (high) (Traditional)
Circulation (poor) (Traditional)
Constipation (adults) (Traditional)
Constipation (children) (Traditional)
Diabetes (Traditional)
Digestion (poor) (Traditional)
Dysmenorrhea (Traditional)
Dyspepsia (Traditional)
Edema (Traditional)
Fatigue (Traditional)
Fibroids (uterine) (Traditional)
Gastritis (Traditional)
Gout (Traditional)
Hair (loss or thinning) (Traditional)
Hypertension (Traditional)
Indigestion (Traditional)
Inflammation (Traditional)
Kidney Stones (Traditional)
Menopause (Traditional)
Menstrual Irregularity (Traditional)
Nausea and Vomiting (Traditional)
Osteoporosis (Traditional)
Pain (general remedies for) (Traditional)

dioscorea is used to support these body systems

Adrenal Cortex (Traditional)
Adrenal Glands (Traditional)
Blood (Traditional)
Breasts (Traditional)
Digestive System (Traditional)
Estrogen (Traditional)
Female Reproductive System (Traditional)
Gall Bladder (Traditional)
Glandular System (Traditional)
Immune System (Traditional)
Joints (Traditional)
Ovaries (Traditional)
Parasympathetic Nervous System (Traditional)
Progesterone (Traditional)
Prostaglandins (Traditional)
Reproductive System (Traditional)
Small Intestines (Traditional)
Spleen (Traditional)
Uterus (Traditional)