Catalase (catalase)
Synopsis of catalase
Catalase is a naturally occurring antioxidant enzyme found in nearly all living organisms exposed to oxygen. It plays a crucial role in cellular defense by breaking down hydrogen peroxide (H₂O₂)—a potentially harmful byproduct of metabolic activity—into water and oxygen. This detoxifying action helps protect cells from oxidative stress, which contributes to aging, inflammation, and degenerative diseases.
Catalase is most concentrated in liver, kidney, and red blood cells, but it is also found in various plants, bacteria, and fungi, and is sometimes supplemented for anti-aging, detoxification, and cellular health purposes.
Key actions of catalase include:
- Neutralizing hydrogen peroxide, preventing oxidative damage to cells and DNA
- Supporting antioxidant defense systems, especially when paired with superoxide dismutase (SOD) and glutathione peroxidase
- Contributing to the longevity and function of cells, particularly in high-turnover tissues like the skin and hair
Health-related uses and benefits:
- Protecting against oxidative stress in aging and chronic illness
- Investigated for its role in delaying hair graying, as hydrogen peroxide accumulation in hair follicles is linked to pigment loss
- Supporting liver detoxification and cellular repair
- Included in some supplements and topical products aimed at anti-aging and vitality
Sources and Supplementation:
- Naturally found in animal liver, wheatgrass, sprouts, and some fermented foods
- Available as oral supplements, though the enzyme form may be degraded in digestion unless enteric-coated or delivered via liposomal or plant-based delivery systems
- Also used topically or in hair care products for potential antioxidant or graying-reversal claims
Historical and Scientific Context:
Catalase was one of the first enzymes ever studied, discovered in the 19th century, with major breakthroughs in enzymology and oxidative biology in the 20th century linking it to the aging process and oxidative stress-related diseases.
While it was not a traditional herb or supplement in historical medicine, foods naturally high in catalase or promoting its activity—like green leafy vegetables, liver, and sprouts—have long been used in traditional healing systems to support detoxification, vitality, and youthful energy.
Today, catalase is often included in anti-aging formulations, antioxidant blends, and hair health supplements, with emerging interest in its role in protecting mitochondria, reducing free radical load, and promoting longevity.
Catalase is used for these health conditions
Aging (prevention) (Scientific)
Cancer Treatment (reducing side effects) (Scientific)
Cataracts (Scientific)
Free Radical Damage (Scientific)
Hearing Loss (Scientific)
Liver Detoxification (Scientific)
Radiation Sickness (Scientific)
Skin Care (general) (Scientific)
