Ampelopsin
Synopsis of Ampelopsin
History
Ampelopsin, also known as dihydromyricetin (DHM), is a natural flavonoid compound primarily extracted from the Japanese raisin tree (Hovenia dulcis) and certain species of the Ampelopsis genus. Historically, Ampelopsin has been revered in traditional East Asian medicine, particularly in Chinese and Korean remedies, for its broad spectrum of health benefits. It was commonly used as a folk remedy to alleviate hangover symptoms, support liver health, and promote detoxification after excessive alcohol consumption. Ancient texts and herbal compendiums document its use to ease symptoms of intoxication, improve energy, and maintain overall vitality.
Beyond its role in managing alcohol-related ailments, Ampelopsin has been employed for its anti-inflammatory, antioxidant, and immune-boosting properties. Traditional healers often prepared decoctions or infusions that blended Ampelopsin-rich herbs with other botanicals such as kudzu root, licorice, and schisandra berries. These combinations were believed to enhance the herb's protective effects on the liver, support digestive health, and improve resilience against fatigue and stress.
Modern research continues to affirm many of these traditional uses, highlighting Ampelopsin’s contribution to liver protection, cognitive function, and cellular defense mechanisms. In contemporary herbal formulations, Ampelopsin is frequently included with complementary ingredients to optimize its efficacy for detoxification, metabolic support, and antioxidative action. Its enduring legacy in both historical and modern wellness underscores its value as a natural remedy, showcasing the remarkable potential of herbal medicine in supporting holistic health.
Traditional and scientific validation
Ampelopsin, also known as dihydromyricetin (DHM), is a natural flavonoid compound primarily extracted from the Japanese raisin tree (Hovenia dulcis) and some species of the Ampelopsis genus. Historically, extracts containing ampelopsin have been utilized in traditional East Asian medicine, particularly for their purported hepatoprotective and detoxifying properties, such as alleviating hangover symptoms and supporting liver health.
Modern scientific research has increasingly focused on ampelopsin’s potential health benefits. In vitro and animal studies suggest that ampelopsin exhibits strong antioxidant, anti-inflammatory, and neuroprotective activities. For example, research published in the Journal of Neuroscience demonstrated that ampelopsin could reduce ethanol-induced neurotoxicity, indicating possible benefits in supporting cognitive function during alcohol exposure. Other preclinical studies have explored its effects on glucose metabolism, lipid regulation, and cardiovascular health, showing promising outcomes in animal models.
While several small-scale human studies have investigated ampelopsin’s effects—particularly regarding its ability to mitigate hangover symptoms and support liver enzymes—comprehensive clinical trials in humans remain limited. Most available human data suggest good tolerability and safety at recommended doses, but more robust, well-controlled studies are needed to conclusively validate its long-term efficacy and mechanisms of action.
Overall, ampelopsin represents a promising natural ingredient with a history of traditional use and encouraging scientific findings. As interest in botanical supplements grows, further research will help clarify its full range of health benefits and potential applications in nutritional products.
Ampelopsin is used for these health conditions
Aging (prevention) (Scientific)
Alzheimer's Disease (Scientific)
Arthritis (Scientific)
Cancer (natural therapy for) (Scientific)
Cancer (prevention) (Scientific)
Cancer Treatment (reducing side effects) (Scientific)
Cardiovascular Disease (Scientific)
Cholesterol (high) (Scientific)
Diabetes (Scientific)
Fatty Liver Disease (Scientific)
Hypertension (Scientific)
Inflammation (Scientific)
Memory and Brain Function (Scientific)
Metabolic Syndrome (Scientific)
Osteoporosis (Scientific)
Rheumatoid Arthritis (Scientific)
Triglycerides (high) (Scientific)
Ampelopsin is used to support these body systems
Circulatory System (Scientific)
Heart (Scientific)
Hepatic System (Scientific)
Immune System (Scientific)
Liver (Scientific)
Mitochondria (Scientific)
