Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Bovine collagen is commonly used in supplements and skincare products aimed at reducing wrinkles and supporting skin health. Scientific studies provide a moderate level of evidence for its efficacy. Collagen is a major structural protein in the skin, giving it strength and elasticity. As we age, endogenous collagen production declines, contributing to wrinkle formation and skin laxity.

Oral supplementation with bovine-derived collagen peptides has been shown in several randomized, placebo-controlled trials to improve skin elasticity, hydration, and reduce wrinkle depth. A 2019 meta-analysis published in Journal of Drugs in Dermatology concluded that oral collagen supplementation increases skin elasticity, hydration, and dermal collagen density. Studies suggest that hydrolyzed collagen peptides are absorbed through the gut and can stimulate fibroblast activity and new collagen synthesis in the skin.

Topically, the benefits are less clear, as intact collagen molecules are generally too large to penetrate the skin barrier. However, some topical products use hydrolyzed forms or combine collagen with other actives to enhance absorption and effect.

In summary, while there is moderate scientific evidence supporting oral bovine collagen supplementation for wrinkle reduction, the mechanism relies on the peptides’ bioavailability and ability to stimulate endogenous collagen production. The evidence for topical bovine collagen is weaker. Overall, bovine collagen’s use for wrinkles is justified with a rating of 3 out of 5 for scientific support.

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