Evidence supporting the use of: Lactobacillus mixed)
For the body system: Vagina

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Lactobacillus species are naturally dominant in the healthy vaginal microbiota, where they play an important role in maintaining the acidic pH and protecting against infections. Scientific research has shown that disruptions in this balance, such as a decrease in Lactobacillus populations, are associated with conditions like bacterial vaginosis and yeast infections. Several clinical studies and systematic reviews have examined the use of orally or intravaginally administered mixed strains of Lactobacillus (e.g., L. crispatus, L. rhamnosus, L. reuteri) for supporting vaginal health. These studies suggest that supplementation can help restore a healthy vaginal microbiome, reduce recurrence rates of bacterial vaginosis, and possibly support recovery from vulvovaginal candidiasis, particularly when used alongside standard treatments. The mechanisms include competitive inhibition of pathogens, production of lactic acid (lowering pH), and modulation of local immune responses. While not all studies show strong benefit, and there is variability in strains and formulations tested, the overall body of evidence supports the use of mixed Lactobacillus probiotic preparations for supporting vaginal health, especially in women prone to recurrent infections. The evidence base is moderate to strong, with ongoing research refining optimal strains, dosing, and delivery methods.

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