Evidence supporting the use of: Vitex negundo
For the body system: Uterus

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Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Vitex negundo, commonly known as the Chinese chaste tree or Nirgundi, has a long history of traditional use in Ayurveda and other folk medicine systems for supporting women’s reproductive health, including the uterus. Traditional healers have employed its leaves, seeds, and roots for the management of menstrual disorders, dysmenorrhea, and to help regulate the menstrual cycle. Its reputed benefits are attributed to its anti-inflammatory, analgesic, and mild hormone-modulating properties.

Scientific research on Vitex negundo is limited with respect to direct effects on the uterus or uterine health in humans. Some animal studies and in vitro experiments suggest anti-inflammatory and analgesic effects, which might indirectly support traditional uses for menstrual discomfort. A few studies have noted possible estrogenic or hormone-balancing effects, but these findings are preliminary and have not led to established clinical evidence for uterine health support. There are no large, high-quality clinical trials confirming its efficacy for uterine health in women.

In summary, Vitex negundo is used to support the uterus primarily based on traditional practices, with limited but suggestive preclinical scientific backing. The overall evidence remains insufficient for firm scientific validation, and its primary justification remains rooted in traditional use.

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