Evidence supporting the use of: Oxytocin
For the body system: Uterus

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Oxytocin is widely recognized in scientific and medical communities for its critical role in supporting the uterus, particularly during labor and postpartum periods. Oxytocin is a peptide hormone produced by the hypothalamus and released from the posterior pituitary gland. Its most well-established function related to the uterus is the stimulation of uterine muscle contractions during childbirth, facilitating labor and delivery. Synthetic oxytocin (often known by the trade name Pitocin) is routinely administered in clinical settings to induce or augment labor in women whose labor is not progressing adequately. It is also used postpartum to help contract the uterus and reduce bleeding, thereby preventing postpartum hemorrhage—a leading cause of maternal mortality worldwide.

Numerous clinical trials and decades of obstetric practice provide robust evidence for oxytocin’s efficacy and safety in these contexts. Its use is recommended by authoritative organizations, including the World Health Organization and the American College of Obstetricians and Gynecologists, for labor induction and postpartum hemorrhage management. The mechanism of action is well understood: oxytocin binds to receptors on uterine smooth muscle cells, triggering contractions. Thus, scientific validation for oxytocin’s use in supporting the uterus is exceptionally strong, making it a mainstay of modern obstetric care.

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Products containing Oxytocin

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