Evidence supporting the use of: Five-leaf Chastetree
For the body system: Uterus
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Five-leaf Chastetree (Vitex negundo) has a long history of use in traditional medicine systems across Asia, particularly in Ayurveda, Siddha, and Unani medicine. Traditionally, various parts of the plant—including leaves, roots, and seeds—are used for their purported benefits on female reproductive health, including support of the uterus. In folk practices, it is believed to help regulate menstrual cycles, alleviate menstrual pain, and promote uterine health. Its use for these purposes is largely based on empirical, anecdotal evidence passed down through generations.
From a scientific standpoint, there is limited direct evidence to validate the specific effects of Five-leaf Chastetree on the uterus. Some preclinical studies suggest that extracts of Vitex negundo possess anti-inflammatory, analgesic, and mild estrogenic or hormone-modulating effects, which could theoretically impact menstrual health or uterine function. However, robust clinical trials in humans are lacking, and the majority of available research does not focus specifically on uterine outcomes. Thus, while the traditional use is well-documented, scientific support remains weak, and most claims are not yet substantiated by high-quality human evidence.
In summary, Five-leaf Chastetree is traditionally used to support the uterus, but its efficacy for this purpose has not been convincingly demonstrated in scientific studies.
Other ingredients that support Uterus
astragalusblack cohosh
chamomile
chaste tree
damiana
dong quai root
fennel
fenugreek
folate
genistein
ginger
ginseng
gotu kola
licorice root
lignans
maca
magnesium
motherwort
parsley
protein
raspberry
rose oil
wild yam
zinc
red clover
squawvine
chickweed
mugwort
anise
blessed thistle
peony
yarrow
root tuber
dioscorea
guelder rose
shepherd's purse
soy isoflavones
Angelica
Alchemilla
Aletris
Anserina
Agnuside
Ashoka
Abuta
Blue Cohosh
Bugbane
Bethroot
Barbasco
Cohosh
Clary sage
Cramp Bark
Casticin
Crinum latifolium
Carthamus
Daidzein
Dong Quai
Diosgenin
Evening Primrose Oil
Estrogen
Folic Acid
Fo-Ti
False Unicorn Root
Giant Trillium
Golden Ragwort
Isoflavones
jasmine
Pennyroyal
Rose
Other body systems supported by Five-leaf Chastetree
BreastsEstrogen
Female Reproductive System
Pituitary
Progesterone
Reproductive System
Uterus