Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Paper mulberry (Broussonetia papyrifera) has been used in traditional medicine systems, especially in East Asia, for treating a variety of ailments, including ulcers. Historical texts and ethnobotanical records describe its use for gastrointestinal issues, such as gastric ulcers and inflammation, in traditional Chinese and Korean medicine. The bark, leaves, and roots have been prepared as decoctions or poultices for this purpose. The attributed benefit is often due to the plant's anti-inflammatory and antimicrobial properties, which are thought to promote healing in ulcerative conditions.

However, scientific evidence supporting these uses is limited. While some laboratory studies have identified antioxidant and anti-inflammatory phytochemicals—such as flavonoids and alkaloids—in Paper mulberry, direct research on its efficacy against ulcers (in animal or human models) remains sparse. The evidence available is mostly preclinical or in vitro, with very few studies exploring the specific anti-ulcer mechanism or clinical effectiveness. Thus, the use of Paper mulberry for ulcers is primarily justified by tradition, and not by robust clinical science.

Overall, while there is a historical basis for using Paper mulberry in the management of ulcers, its efficacy for this purpose has not been substantiated by high-quality scientific studies.

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