Evidence supporting the use of: Lactobacillus (mixed)
For the health condition: Thrush

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus (mixed strains) is used to support or treat thrush (oral or vaginal candidiasis) based on scientific evidence, although the quality and consistency of the evidence is moderate and not definitive. Clinical studies and reviews suggest that certain Lactobacillus strains can help restore the balance of normal microbiota, which may inhibit the growth of Candida species responsible for thrush. Lactobacilli produce substances such as lactic acid and hydrogen peroxide that create an acidic environment, unfavorable to Candida overgrowth. Some randomized controlled trials have shown that oral or vaginal administration of Lactobacillus can reduce the recurrence of vulvovaginal candidiasis and may help resolve symptoms more quickly when used alongside antifungal medications. However, results are variable, and not all studies show significant benefit. The efficacy seems to depend on factors like the specific Lactobacillus strain used, dosage, and mode of administration. Meta-analyses and systematic reviews generally conclude that probiotics, including Lactobacillus, may be a useful adjunct to conventional therapy for thrush, but more high-quality studies are needed to establish standardized protocols and confirm clinical benefits. Overall, the use of Lactobacillus for thrush is supported by a moderate level of scientific evidence, but it is not considered a standalone treatment.

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