Evidence supporting the use of: Boron (various)
For the body system: Testes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Boron is a trace mineral that has been investigated for its role in supporting male reproductive health, including testicular function. Several scientific studies have explored boron's influence on steroid hormone metabolism, particularly testosterone. Research indicates that boron supplementation (typically at doses around 6 mg/day) can increase serum testosterone levels in men, which may be relevant to testicular function since the testes are the primary site of testosterone synthesis. A 2011 study (Naghii et al.) found that healthy males who supplemented with boron for one week experienced significant increases in free testosterone and decreases in estradiol. Additionally, boron may reduce levels of sex hormone-binding globulin (SHBG), further increasing the availability of free testosterone.

Although the evidence is promising, most of the human studies have been small and short in duration. There is some mechanistic support from animal studies, showing boron's involvement in testicular steroidogenesis and antioxidant defense within testicular tissue. Traditional systems of medicine have not historically emphasized boron specifically for male reproductive health, so the rationale for its use is based mainly on emerging scientific data. While boron appears to support aspects of testicular function via hormonal modulation, more large-scale and long-term human studies are needed to fully confirm its efficacy and safety for this purpose.

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