Evidence supporting the use of: Urolithin A
For the body system: Structural System
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Urolithin A is a metabolite produced by gut bacteria from ellagitannins, compounds found in pomegranates and some other fruits. Recent scientific research has explored Urolithin A’s effects on the structural system, particularly skeletal muscle and bone health. Preclinical studies have shown that Urolithin A can promote mitophagy (the selective degradation of damaged mitochondria), leading to improved mitochondrial function in muscle cells. Human clinical trials, though limited, indicate that supplementation with Urolithin A can improve muscle endurance and strength in older adults, which is relevant to the structural system's integrity and function.
Additionally, some animal studies suggest that Urolithin A may have a positive impact on bone health by reducing inflammation and oxidative stress, factors that contribute to bone degeneration. However, direct evidence in humans regarding bone density or fracture prevention is currently lacking. There is no significant historical or traditional use of Urolithin A for structural system support, as it is a relatively newly identified compound in scientific research.
In summary, the use of Urolithin A for supporting the structural system is grounded in emerging scientific evidence, particularly in relation to muscle health and mitochondrial function. However, larger and longer-term human studies are needed to fully validate its efficacy for broader aspects of the structural system such as bone health. The current evidence justifies a moderate rating.
Other ingredients that support Structural System
alfalfabayberry
bovine gelatin
burdock
calcium
cartilage
chondroitin
cissus quadrangularis
collagen
copper
turmeric
devil's claw
fish protein
gelatin
glucosamine
hyaluronic acid
l-leucine
l-proline
magnesium
marine lipid
methylsulfonylmethane (MSM)
microcrystalline hydroxyapatite concentrate (MCHC)
milk
moringa
n-acetyl-glucosamine
omega-3 fatty acids
phosphorus
protein
silicon
slippery elm bark
strontium
Urolithin A
vitamin B
vitamin C
vitamin D
vitamin K
water
zinc
chickweed
sodium salt
eucommia
trace minerals
yucca
arnica
Algal protein
Beef
Bovine Protein
Bone Protein
Bee products
Creatine
Egg
Eucommia ulmoides
Elastin
fibroblast growth factor
Glycine
Glycosaminoglycans
Other body systems supported by Urolithin A
BrainCirculatory System
Gastrointestinal Tract
Heart
Mitochondria
Muscles
Structural System