Evidence supporting the use of: Glucosamine (unspecified)
For the body system: Structural System
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Glucosamine is a naturally occurring compound found in cartilage, the tissue that cushions joints. It is commonly used as a dietary supplement to support joint health, which is a key component of the structural system of the body. Scientific studies have primarily focused on glucosamine’s role in managing symptoms of osteoarthritis, especially in the knees. Some randomized controlled trials and meta-analyses suggest that glucosamine sulfate may provide modest relief from osteoarthritis symptoms, such as pain and reduced joint function, although results across studies are mixed. The efficacy appears greater in products containing glucosamine sulfate rather than glucosamine hydrochloride. Major medical organizations, such as the American College of Rheumatology, generally consider glucosamine as an option for individuals seeking alternative or adjunct treatments, though they do not universally recommend its use due to variable results and questions about clinical significance. The mechanism of action is thought to involve support for cartilage repair and possible anti-inflammatory effects. While glucosamine is widely used and considered safe for most people, its benefits are best supported for mild to moderate osteoarthritis rather than for prevention or for broader “structural system” support. In summary, there is moderate scientific evidence justifying glucosamine’s use for joint health within the structural system, but its effectiveness is not unequivocally established and may vary by individual.
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alfalfabayberry
bovine gelatin
burdock
calcium
cartilage
chondroitin
cissus quadrangularis
collagen
copper
turmeric
devil's claw
fish protein
gelatin
glucosamine
hyaluronic acid
l-leucine
l-proline
magnesium
marine lipid
methylsulfonylmethane (MSM)
microcrystalline hydroxyapatite concentrate (MCHC)
milk
moringa
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omega-3 fatty acids
phosphorus
protein
silicon
slippery elm bark
strontium
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vitamin B
vitamin C
vitamin D
vitamin K
water
zinc
chickweed
sodium salt
eucommia
trace minerals
yucca
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fibroblast growth factor
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