Evidence supporting the use of: Glucosamine (mixed)
For the body system: Structural System

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Glucosamine is a naturally occurring compound found in cartilage, the tissue that cushions joints. It is commonly used as a dietary supplement to support joint health and is often marketed for conditions like osteoarthritis, which affects the structural (musculoskeletal) system. Scientific validation for glucosamine's effectiveness in supporting joint health comes primarily from clinical trials and systematic reviews, though the evidence is mixed.

Several randomized controlled trials and meta-analyses have investigated glucosamine (often in combination with chondroitin) for osteoarthritis, particularly of the knee. Some studies report modest improvements in pain and function compared to placebo, while others find little to no benefit. The 2010 American College of Rheumatology guidelines do not recommend glucosamine for osteoarthritis due to inconsistent evidence, but some patients report subjective improvement. The supplement appears to be safe for most people, with few reported side effects.

Glucosamine is widely used in traditional and complementary medicine for joint support, but its primary justification today is based on scientific research into its potential to slow cartilage degeneration and reduce symptoms of osteoarthritis, thereby supporting the structural system. The overall quality of evidence is moderate, and its effectiveness may vary among individuals, leading to a rating of 3 out of 5.

More about Glucosamine (mixed)
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Other body systems supported by Glucosamine (mixed)

Joints
Skeletal System (Bones)
Spinal Disks
Structural System

Products containing Glucosamine (mixed)

We currently have no products on Caring Sunshine that contain this ingredient.