Evidence supporting the use of: Magnesium citrate malate
For the health condition: Stress

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Magnesium citrate malate is a chelated form of magnesium often used as a dietary supplement to address magnesium deficiency. While magnesium as a nutrient has been studied for its potential role in modulating the body's stress response, the evidence directly supporting the use of magnesium citrate malate for stress is limited but suggestive. Several studies have shown that magnesium plays a role in the regulation of the HPA (hypothalamic–pituitary–adrenal) axis and may influence neurotransmitters associated with mood and stress, such as GABA. Lower magnesium levels have been correlated with increased stress and anxiety in observational studies. Some randomized controlled trials (RCTs) using various magnesium salts (not always specifically citrate malate) have found modest reductions in subjective stress and anxiety, particularly in individuals with suboptimal magnesium status. However, the quality of evidence is mixed, with many studies being small, short-term, or not specific to magnesium citrate malate. No large-scale trials have specifically evaluated magnesium citrate malate for stress reduction. Thus, while biological plausibility and some clinical evidence exist for magnesium in general, the evidence for this specific form and for the treatment of stress remains limited, warranting a rating of 2 out of 5 for evidence strength.

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alpha-pinene
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benegut perilla (proprietary)
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dong quai root
eleuthero
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish protein
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gardenia
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green tea
guayusa
heartwood
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hops
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kava root
kudzu
l-ornithine
l-taurine
l-theanine
l-tryptophan
l-tyrosine
lactium casein decapeptide
lactobacillus brevis
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lavender
lentinula edodes mycelia
lion's mane
liquid liver fractions
maca
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magnolia
matcha
melatonin
mint
motherwort
muira puama
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oat
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peppermint oil
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phosphatidylserine
phospholipids
pine bark
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quail egg
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rhodiola
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valerian root
velvet bean
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Products containing Magnesium citrate malate

We currently have no products on Caring Sunshine that contain this ingredient.