Evidence supporting the use of: Chaste tree
For the body system: Specific Hormones

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Chaste tree (Vitex agnus-castus) is commonly used to support the hormonal system, particularly in relation to female reproductive health. Scientific studies have investigated its effects on the hypothalamic-pituitary-gonadal axis, with evidence suggesting that chaste tree may influence levels of prolactin and help restore hormonal balance. Clinical trials have shown that chaste tree extract can reduce symptoms of premenstrual syndrome (PMS), including breast pain, irritability, and mood swings. For instance, a 2012 Cochrane review found moderate evidence that Vitex agnus-castus is more effective than placebo in alleviating PMS symptoms. The mechanism is thought to involve dopaminergic compounds in the fruit that inhibit prolactin release from the pituitary gland, potentially benefiting women with luteal phase defects and mild hyperprolactinemia.

While chaste tree has been used traditionally for centuries for menstrual and fertility-related issues, its modern use is also supported by clinical research. The majority of studies focus on PMS and cyclical mastalgia; evidence for other hormone-related uses, such as menopausal symptoms or fertility enhancement, is less robust but remains an area of active research. Overall, the use of chaste tree for supporting the hormonal (endocrine) system, particularly in women with PMS or mild prolactin-related disturbances, is justified by both tradition and a moderate level of scientific validation.

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