Evidence supporting the use of: Sassafras
For the health condition: Sore Throat

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Sassafras (Sassafras albidum) has a long history of use in North American traditional medicine, including by Indigenous peoples and later by European settlers. Traditionally, sassafras root bark and leaves were used in teas or decoctions to treat a variety of ailments, including sore throat, due to its perceived soothing and anti-inflammatory properties. Historical herbal texts and folklore mention its use for throat irritation and as a general remedy for colds and respiratory discomfort. However, modern scientific research does not provide robust evidence supporting its efficacy for sore throat treatment. The primary active compound in sassafras, safrole, has been shown to have potential toxicity and carcinogenicity in animal studies, leading to regulatory restrictions on its use in food and medicine. As a result, sassafras is no longer widely recommended or used in contemporary herbal practice for sore throat. Overall, the use of sassafras for sore throat is justified primarily by traditional practices rather than scientific validation, and the quality of supporting evidence is low.

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