Evidence supporting the use of: Quercetin
For the health condition: Sneezing

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Quercetin is a plant flavonoid found in many fruits and vegetables, and it has been studied for its anti-inflammatory and antihistamine properties. Its use for sneezing, particularly sneezing associated with allergic rhinitis (hay fever), is grounded primarily in its ability to inhibit the release of histamine from mast cells and basophils. Histamine is a key mediator in allergic responses, often responsible for symptoms such as sneezing, runny nose, and itching.

Some preliminary laboratory and animal studies have shown that quercetin can stabilize mast cells and reduce the release of histamine and other inflammatory mediators. A few small human studies have explored the effect of quercetin on allergic rhinitis symptoms, including sneezing. For example, a randomized controlled trial published in 2016 found that quercetin supplementation reduced some allergy symptoms, but the evidence remains limited by small sample sizes and methodological weaknesses.

Overall, while there is a plausible scientific basis for quercetin's use in reducing sneezing related to allergies, the clinical evidence is not robust. Larger, high-quality human trials are needed to confirm its efficacy. Therefore, its use for sneezing has some scientific support, but the strength of the evidence is moderate at best.

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quercetin