Galactosidase, specifically the enzyme β-galactosidase (commonly referred to as lactase when used in dietary supplements), is scientifically validated for its role in supporting the small intestine by aiding in the digestion of lactose, the primary sugar in milk and dairy products. In individuals with lactose intolerance, the small intestine produces insufficient amounts of lactase, leading to gastrointestinal symptoms such as bloating, cramps, and diarrhea when dairy is consumed. Oral supplementation with β-galactosidase (lactase) is well-documented in clinical research to improve lactose digestion and reduce these symptoms.

Multiple clinical trials and systematic reviews have demonstrated that exogenous lactase supplements can significantly enhance lactose tolerance in lactose-intolerant individuals. For example, a meta-analysis published in Alimentary Pharmacology & Therapeutics (2005) found that lactase supplementation was effective in decreasing symptoms and improving digestive comfort in affected patients. The mechanism is straightforward: orally ingested β-galactosidase breaks down lactose into glucose and galactose in the small intestine, which can then be absorbed without causing the typical adverse symptoms.

Therefore, the use of galactosidase/lactase as a dietary supplement is supported by substantial scientific evidence for its efficacy in aiding small intestine function specifically in the context of lactose digestion.