Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Alpha-galactosidase is an enzyme that specifically breaks down complex carbohydrates, such as raffinose and stachyose, found in legumes and certain vegetables. These carbohydrates are otherwise poorly digested in the human small intestine because endogenous digestive enzymes are insufficient for their complete breakdown. As a result, these undigested carbohydrates pass into the colon, where they are fermented by gut bacteria, leading to gas production and symptoms like bloating and flatulence.

The use of alpha-galactosidase as a digestive aid has scientific validation, particularly in the context of supporting digestive comfort and function in the small intestine. Several clinical studies have demonstrated that supplementation with alpha-galactosidase can significantly reduce symptoms of gas and bloating after consuming foods rich in oligosaccharides. For instance, randomized, placebo-controlled trials have shown that individuals taking alpha-galactosidase with meals reported fewer gastrointestinal symptoms compared to those taking a placebo.

While alpha-galactosidase does not address underlying disease of the small intestine, its mechanism of action directly supports the digestive process in this part of the gastrointestinal tract. It helps to break down specific carbohydrates before they reach the colon, thereby reducing potential discomfort. The overall evidence base supports its targeted use for individuals experiencing gas and bloating related to carbohydrate digestion, with a robust scientific foundation for this application.

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Products containing alpha-galactosidase

Nature's Sunshine Proactazyme®