Evidence supporting the use of: Ceramide
For the health condition: Skin (dry and/or flaky)
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Ceramides are a class of lipid molecules naturally found in high concentrations within the stratum corneum, the outermost layer of the skin. Scientific research strongly supports their role in maintaining skin barrier integrity and preventing transepidermal water loss (TEWL). Multiple studies have demonstrated that individuals with dry, flaky, or atopic skin conditions often have reduced levels of ceramides in their skin, correlating with increased barrier dysfunction and dehydration. Topical application of ceramide-containing creams or lotions has been shown in clinical trials to improve skin hydration, reduce TEWL, and alleviate symptoms of dryness and flakiness.
Several randomized controlled trials and systematic reviews confirm the efficacy of ceramide-containing formulations in both healthy individuals and those with dermatological conditions like atopic dermatitis or eczema. These products can replenish the skin’s natural ceramide content, thereby restoring barrier function and moisture retention. The mechanism is well understood: ceramides fill the spaces between skin cells, forming a protective layer that limits water loss and shields the skin from environmental irritants.
In summary, ceramides are a scientifically validated ingredient for supporting and treating dry and/or flaky skin, with robust evidence for their effectiveness and a clear understanding of their biological role.
Other ingredients used for Skin (dry and/or flaky)
aloe veraalpha-linolenic acid (ALA)
beeswax
biotin
borage oil
colostrum
evening primrose oil
gooseberry
linoleic acid (LA)
magnesium
omega-3 fatty acids
rehmannia glutinosa
silicon
vitamin A
vitamin E
zinc
chickweed
swertia
birch
sea salt
Alpha Hydroxy Acids
American Liverleaf
Allantoin
Acemannan
Argan nut oil
Butter
Borage
Cod Liver Oil
Cape Aloe
Cocoa Butter
Cowslip
Chestnut
Castile Soap
Emu Oil
Evening Primrose Oil
Ficus religiosa
Glycolic acid
Glyceryl oleate
Heartsease
Oak
Orchid
Spikenard
Silk protein
Other health conditions supported by Ceramide
Aging (prevention)Cancer (natural therapy for)
Eczema
Inflammation
Psoriasis
Skin (dry and/or flaky)
Skin Care (general)
Wrinkles