Evidence supporting the use of: Panthenol
For the health condition: Skin Care (general)
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Panthenol, also known as provitamin B5, is widely used in skin care due to its well-documented moisturizing, soothing, and barrier-supporting properties. Several clinical and preclinical studies have demonstrated its efficacy in improving skin hydration, reducing transepidermal water loss, and enhancing skin barrier function. Panthenol is readily absorbed by the skin and converted to pantothenic acid, a component essential for the synthesis of coenzyme A, which is involved in lipid metabolism and skin regeneration.
Research has shown that topical application of panthenol can accelerate wound healing, reduce inflammation, and alleviate symptoms of irritation, making it valuable not only for general skin care but also for the management of minor skin injuries, dermatitis, and other conditions characterized by compromised skin barrier. In addition, panthenol has been found to improve skin softness and elasticity, likely due to its humectant properties, which help retain moisture within the stratum corneum.
Multiple peer-reviewed studies and dermatological reviews—such as those found in the Journal of Dermatological Treatment and Skin Pharmacology and Physiology—support these claims, providing a solid scientific basis for panthenol’s inclusion in a wide array of skin care products, from moisturizers and serums to after-sun lotions. Overall, the use of panthenol in general skin care is strongly validated by scientific evidence.
Other ingredients used for Skin Care (general)
aloe veraanthocyanins
apple
apricot
astaxanthin
beeswax
beet
beta-carotene
black currant
radish
sesame
bovine gelatin
catalase
colostrum
cryptoxanthin
cucumber
d-alpha tocopherol
dog rose
heartwood
hyaluronic acid
l-cysteine
l-glutathione
l-histidine
linoleic acid (LA)
lovage
lychee
magnesium
mango
mixed carotenoids
oat
omega-3 fatty acids
pumpkin
redcurrant
silicon
keratin
spinach
starch
tomato
almond fruit
Urolithin A
vitamin A
vitamin C
vitamin E
watercress
watermelon
zinc
sarsaparilla
red clover
chickweed
oryza
root tuber
birch
dulse leaf
camphor oil
goji berry
amaranth
sea salt
3,3'-dihydroxy-B-carotene-4,4'-dione
Alpha-terpineol
Azelaic acid
Arbutin
Avocado
Anserina
Ascophyllum nodosum
Alpha Hydroxy Acids
Asam gelugor
Allantoin
anthocyanidins
Algal protein
Argan nut oil
Abalone
Behenic Acid
Biopeptide
Black spruce
beta-zeacarotene
Brassica
Bisabolene
Butternut
Borage
Bottle gourd
Bird's nest
California chia
Chervil
Carnosine
Candelilla wax
Cocoa Butter
Cereal grass
Citral
Castile Soap
Copaiba Oil
Currant
Dunaliella salina
David's Milkberry
Dulse
Egg
Emu Oil
Flavans
Geraniol
Glycolic acid
Glyceryl oleate
Gac
Glucosylceramide
Glycosylceramides
Heartsease
Himalayan Salt
Oak
Orchid
Rose
Snakeroot (unspecified)
Silk protein
silica
vegetable oil
Other health conditions supported by Panthenol
AbrasionsBlisters
Burns and Scalds
Cuts
Dermatitis
Diaper Rash
Eczema
Lesions
Scars / Scar Tissue
Scratches and Abrasions
Skin (dry and/or flaky)
Skin Care (general)
Sunburn
Wounds and Sores