Evidence supporting the use of: Glycosylceramides
For the health condition: Skin Care (general)
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Glycosylceramides are a class of lipid molecules found naturally in plant and animal cell membranes and have gained attention in dermatology and skin care primarily due to their role in the structure and function of the skin barrier. Scientific studies have demonstrated that glycosylceramides, particularly those derived from plants such as wheat and konjac, can help improve skin hydration and barrier function when taken orally or applied topically. The mechanism is believed to involve the enhancement of stratum corneum ceramide content, which reduces transepidermal water loss and supports skin integrity.
Clinical trials have shown that oral supplementation with plant-derived glycosylceramides can lead to measurable improvements in skin moisture and elasticity in healthy adults and individuals with dry skin conditions. For example, a 2018 randomized, double-blind, placebo-controlled study found that oral wheat extract oil rich in glycosylceramides significantly improved skin hydration and reduced roughness compared to placebo. Other in vitro and animal studies also support the role of glycosylceramides in maintaining skin barrier function.
While more high-quality, large-scale human studies are needed to establish definitive efficacy and optimal dosing, the current scientific evidence suggests a beneficial role of glycosylceramides in supporting general skin health, particularly by enhancing hydration and barrier properties.
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apple
apricot
astaxanthin
beeswax
beet
beta-carotene
black currant
radish
sesame
bovine gelatin
catalase
colostrum
cryptoxanthin
cucumber
d-alpha tocopherol
dog rose
heartwood
hyaluronic acid
l-cysteine
l-glutathione
l-histidine
linoleic acid (LA)
lovage
lychee
magnesium
mango
mixed carotenoids
oat
omega-3 fatty acids
pumpkin
redcurrant
silicon
keratin
spinach
starch
tomato
almond fruit
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vitamin A
vitamin C
vitamin E
watercress
watermelon
zinc
sarsaparilla
red clover
chickweed
oryza
root tuber
birch
dulse leaf
camphor oil
goji berry
amaranth
sea salt
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Ascophyllum nodosum
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anthocyanidins
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Argan nut oil
Abalone
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Biopeptide
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beta-zeacarotene
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Bisabolene
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California chia
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Cereal grass
Citral
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Dunaliella salina
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