Evidence supporting the use of: Glucosylceramide
For the health condition: Skin Care (general)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Glucosylceramide is a type of glycosphingolipid found in the outermost layer of the skin (stratum corneum) and is important for maintaining the skin’s barrier function and hydration. Scientific studies, especially from Japan and other East Asian countries, have investigated both topical and oral supplementation of plant-derived glucosylceramides for skin health. Several randomized, placebo-controlled trials have demonstrated that oral glucosylceramide extracted from plants like rice or konjac can improve skin hydration, reduce transepidermal water loss (TEWL), and help relieve symptoms of dry skin in healthy adults and individuals with mild eczema. The mechanism is believed to involve the upregulation of natural ceramide production and enhanced skin barrier repair.

Topically, glucosylceramide is included in some moisturizers and skincare formulations to support and replenish the skin’s lipid barrier. Scientific evidence for topical efficacy is less robust than for oral supplementation, but some in vitro and clinical studies support its moisturizing and barrier-strengthening properties.

However, while the evidence is promising, most studies are small and short-term, and there is heterogeneity in populations, dosages, and formulations. The ingredient is not a primary treatment for skin diseases but may be a supportive measure for general skin hydration and barrier function. Overall, the use of glucosylceramide for skin care is supported by scientific evidence, but larger and longer-term studies are needed to fully validate its effectiveness.

More about Glucosylceramide
More about Skin Care (general)

Other health conditions supported by Glucosylceramide

Inflammation
Psoriasis
Skin Care (general)

Products containing Glucosylceramide

We currently have no products on Caring Sunshine that contain this ingredient.