Evidence supporting the use of: Ceramide
For the health condition: Skin Care (general)
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Ceramides are lipid molecules naturally found in the stratum corneum, the outermost layer of the skin, where they play a critical role in maintaining the skin’s barrier function and retaining moisture. Scientific studies have demonstrated that individuals with various skin conditions, such as atopic dermatitis, psoriasis, and dry skin, often exhibit reduced levels of ceramides. Topical application of ceramide-containing moisturizers has been shown in multiple clinical trials to enhance barrier repair, reduce transepidermal water loss, and improve overall skin hydration.
Notably, a review published in the Journal of the American Academy of Dermatology (2018) concluded that ceramide-dominant formulations are effective in managing symptoms of eczema and dry skin. Another systematic review in Dermatologic Therapy (2020) highlighted the beneficial effects of ceramide-based products in both healthy individuals and those with barrier-impaired skin. These products are well-tolerated and have a favorable safety profile, making them a mainstay in modern skincare regimens aimed at barrier support and hydration.
In summary, the use of ceramides in general skin care is strongly supported by scientific evidence, particularly for their role in barrier function and moisture retention. Their inclusion in topical formulations is considered both rational and effective based on current clinical data.
Other ingredients used for Skin Care (general)
aloe veraanthocyanins
apple
apricot
astaxanthin
beeswax
beet
beta-carotene
black currant
radish
sesame
bovine gelatin
catalase
colostrum
cryptoxanthin
cucumber
d-alpha tocopherol
dog rose
heartwood
hyaluronic acid
l-cysteine
l-glutathione
l-histidine
linoleic acid (LA)
lovage
lychee
magnesium
mango
mixed carotenoids
oat
omega-3 fatty acids
pumpkin
redcurrant
silicon
keratin
spinach
starch
tomato
almond fruit
Urolithin A
vitamin A
vitamin C
vitamin E
watercress
watermelon
zinc
sarsaparilla
red clover
chickweed
oryza
root tuber
birch
dulse leaf
camphor oil
goji berry
amaranth
sea salt
3,3'-dihydroxy-B-carotene-4,4'-dione
Alpha-terpineol
Azelaic acid
Arbutin
Avocado
Anserina
Ascophyllum nodosum
Alpha Hydroxy Acids
Asam gelugor
Allantoin
anthocyanidins
Algal protein
Argan nut oil
Abalone
Behenic Acid
Biopeptide
Black spruce
beta-zeacarotene
Brassica
Bisabolene
Butternut
Borage
Bottle gourd
Bird's nest
California chia
Chervil
Carnosine
Candelilla wax
Cocoa Butter
Cereal grass
Citral
Castile Soap
Copaiba Oil
Currant
Dunaliella salina
David's Milkberry
Dulse
Egg
Emu Oil
Flavans
Geraniol
Glycolic acid
Glyceryl oleate
Gac
Glucosylceramide
Glycosylceramides
Heartsease
Himalayan Salt
Oak
Orchid
Rose
Snakeroot (unspecified)
Silk protein
silica
vegetable oil
Other health conditions supported by Ceramide
Aging (prevention)Cancer (natural therapy for)
Eczema
Inflammation
Psoriasis
Skin (dry and/or flaky)
Skin Care (general)
Wrinkles