Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Vitamin D (including both D2 and D3 forms, hence "mixed") is strongly supported by scientific evidence for its essential role in supporting the skeletal system and bone health. Vitamin D facilitates intestinal absorption of calcium and phosphate, minerals critical for the formation and maintenance of healthy bones. Deficiency in vitamin D can lead to decreased calcium absorption, resulting in rickets in children (characterized by impaired bone mineralization and skeletal deformities) and osteomalacia or osteoporosis in adults (leading to weakened bones and increased fracture risk).

Numerous randomized controlled trials and meta-analyses have established that adequate vitamin D levels are necessary to maintain bone density and reduce the risk of fractures, particularly in older adults. Clinical guidelines from major health organizations, such as the Institute of Medicine and the Endocrine Society, recommend vitamin D supplementation for individuals at risk of deficiency to support skeletal health. Vitamin D supplementation is often paired with calcium to maximize benefits for bone strength.

In summary, the use of vitamin D to support the skeletal system is scientifically validated, with a well-understood mechanism of action and a substantial body of clinical evidence confirming its effectiveness in the prevention and treatment of bone-related disorders.

More about Vitamin D (mixed)
More about Skeletal System (Bones)

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Other body systems supported by Vitamin D (mixed)

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