Calcium and magnesium are both essential minerals that play critical roles in supporting the skeletal system. Calcium is the primary mineral found in bones and is necessary for bone structure and strength. Scientific studies have consistently shown that adequate calcium intake, especially in combination with vitamin D, helps maintain bone mineral density and reduce the risk of osteoporosis and fractures, particularly in older adults and postmenopausal women.

Magnesium, while present in smaller amounts in bone, is involved in bone formation and influences the activity of osteoblasts and osteoclasts, the cells responsible for building up and breaking down bone. Magnesium deficiency has been linked to decreased bone mass, increased inflammation, and higher risk of osteoporosis. Some evidence suggests that magnesium supplementation can have a modest positive effect on bone mineral density, especially in individuals with low baseline magnesium levels.

Citrate forms of minerals, such as calcium magnesium citrate, are often used in supplements because they are more easily absorbed in the digestive tract compared to other forms, such as oxides or carbonates. While most clinical trials focus on calcium (with or without vitamin D), the inclusion of magnesium is increasingly recognized as important for overall bone health.

In summary, there is substantial scientific validation that calcium and magnesium contribute to bone health, and supplementation can be beneficial in individuals at risk of deficiency or osteoporosis.