Evidence supporting the use of: Five-leaf Chastetree
For the health condition: Sex Drive (low)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Five-leaf Chastetree (Vitex negundo) has a long history of use in traditional medicine systems, particularly in Ayurveda, Unani, and various Southeast Asian folk practices. Traditionally, it has been used to treat a range of conditions, including reproductive and sexual health issues. Some ethnobotanical records suggest its use as an aphrodisiac or as a remedy for low sex drive, particularly in men. These uses are based largely on anecdotal evidence and historical accounts rather than rigorous scientific study.

Modern scientific research on Five-leaf Chastetree's efficacy for improving libido or sexual function is extremely limited. Most studies have focused on related species such as Vitex agnus-castus (Chasteberry), which is more commonly linked to hormonal modulation, especially in women. There are a few preclinical studies on Vitex negundo indicating potential androgenic or libido-enhancing effects in animal models, but these results are preliminary and not well replicated or validated in humans. No high-quality clinical trials have confirmed its benefits for sexual desire. Therefore, current support for its use in low sex drive is primarily traditional, with low to moderate evidence from poorly controlled studies.

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