Evidence supporting the use of: Jujubosides
For the body system: Serotonin

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Table of Contents

Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Jujubosides are saponins extracted from the seeds of Ziziphus jujuba var. spinosa, commonly known as jujube. Traditionally, these seeds have been used in East Asian medicine for their sedative and anxiolytic effects, and are a component of formulas prescribed for insomnia and nervous conditions. The link to the "serotonin body system" is indirect; traditional texts and ethnobotanical reports do not specifically mention serotonin, but rather reference calmness, improved sleep, and reduced anxiety.

Modern scientific studies have begun to investigate the possible mechanisms of jujubosides, including their effects on neurotransmitter systems. Some preclinical research in rodents suggests that jujubosides may modulate levels of neurotransmitters like serotonin, GABA, and dopamine in the brain, which could underlie their calming effects. However, direct clinical evidence in humans showing that jujubosides specifically support or modulate the serotonin system is lacking. The bulk of evidence remains preclinical, and much of the traditional use is not explicitly tied to serotonin by historic practitioners.

In summary, jujubosides are used traditionally to support relaxation and sleep, which may involve the serotonin system, but this link is not robustly established by either traditional doctrine or strong scientific evidence. Thus, use of jujubosides for the "serotonin body system" is primarily justified by tradition, with a low to moderate level of supporting evidence.

More about Jujubosides
More about Serotonin

Other body systems supported by Jujubosides

Brain
GABA
Nerves
Parasympathetic Nervous System
Senses
Serotonin

Products containing Jujubosides

We currently have no products on Caring Sunshine that contain this ingredient.