Evidence supporting the use of: Convolvulus prostratis
For the body system: Serotonin

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Convolvulus prostratus (commonly known as Shankhpushpi) has a long history of use in traditional Ayurvedic medicine, primarily as a "medhya rasayana" (nootropic herb) for supporting cognitive function, memory, and mental well-being. Its traditional applications include alleviating anxiety, stress, and insomnia, and enhancing cognitive performance. While these effects suggest an indirect influence on neurotransmitter systems such as serotonin, the historical texts do not explicitly mention serotonin, as the neurotransmitter was not discovered until the 20th century. However, the calming and mood-stabilizing effects described in Ayurveda are consistent with herbs that may modulate serotonin or related pathways.

Scientific studies on Convolvulus prostratus are limited, but a few animal studies suggest potential antidepressant and anxiolytic effects. For instance, some preclinical research indicates that extracts of the plant may influence neurotransmitters including serotonin, dopamine, and noradrenaline in the brain. However, these studies are preliminary and have not established a direct mechanism or clinical efficacy in humans.

In summary, the use of Convolvulus prostratus to support the "serotonin body system" is primarily justified by traditional use, with some suggestive but not definitive preclinical evidence. There is a lack of robust, high-quality clinical data supporting its direct effect on serotonin in humans.

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