Evidence supporting the use of: Zeaxanthin
For the body system: Senses

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Zeaxanthin is a carotenoid found in high concentrations in the retina, particularly the macula, of the human eye. Its primary role in the body is to function as an antioxidant and to filter high-energy blue light, which can cause oxidative stress and damage to retinal cells. Several observational and interventional studies have investigated the relationship between zeaxanthin (often alongside lutein) and visual health. Notably, the Age-Related Eye Disease Study 2 (AREDS2), a large randomized controlled trial, demonstrated that supplementation with zeaxanthin and lutein reduced the risk of progression to advanced age-related macular degeneration (AMD), a leading cause of vision loss in older adults. Additionally, epidemiological research suggests higher dietary intake of zeaxanthin is associated with a lower risk of cataracts and improved visual performance, such as glare recovery and contrast sensitivity. While zeaxanthin is generally considered beneficial for maintaining eye health and supporting the "Senses" body system—specifically vision—the evidence for benefits in senses like hearing or smell is lacking. Overall, the scientific evidence supporting zeaxanthin's role in supporting visual function is strong, especially in the context of age-related visual decline, justifying its use in supplements targeting the Senses body system.

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Other body systems supported by zeaxanthin

Eyes
Senses