Evidence supporting the use of: Comfrey
For the health condition: Scratches and Abrasions
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Comfrey for Scratches and Abrasions: Evidence Overview
Comfrey (Symphytum officinale) has a long history of use in traditional medicine for wound healing, including minor scratches and abrasions. Its use is not only traditional but also supported by a moderate body of scientific evidence.
Modern research has identified several active constituents in comfrey, such as allantoin, rosmarinic acid, and mucilage, which contribute to its purported healing effects. Allantoin, in particular, is known to promote cell proliferation and support tissue regeneration, making it beneficial for superficial skin injuries.
Clinical studies and reviews have evaluated topical comfrey preparations (creams, ointments, or gels) for their efficacy in treating minor wounds, abrasions, and inflammatory skin conditions. A 2013 systematic review published in Phytotherapy Research concluded that comfrey extract significantly accelerates wound healing and reduces symptoms like redness and swelling when compared with placebo. Another randomized controlled trial demonstrated improved healing rates of abrasions in participants using comfrey ointment versus control treatments.
However, comfrey contains pyrrolizidine alkaloids (PAs) that are hepatotoxic if absorbed systemically or ingested. As such, only PA-free topical products are recommended, and use should be limited to unbroken skin or superficial wounds to avoid absorption risks.
In summary, while traditional use is well established, there is also moderate scientific validation for comfrey's effectiveness in supporting the healing of scratches and abrasions when applied topically and appropriately.
Other ingredients used for Scratches and Abrasions
aloe verabayberry
beeswax
bisabolol
black walnut
chamomile
turmeric
dyer’s woad root
iodine
Japanese sophora
lauric acid
mucin
protease
slippery elm bark
vitamin C
zinc
parthenium
chickweed
paederia foetida
lilac
yarrow
moss
oriental arborvitae
tartarian aster
camphor oil
cleavers
wood betony
white oak
melaleuca alternifolia
geranium
arnica
Asclepias cordifolia
acacia
Agrimony
Antirrhinum majus
Achyranthes
Anserina
Anemone
Aquilegia formosa
Allantoin
Alkanet
Acemannan
Abuta
Alkanna
Bee Propolis
Babchi
Bai Ji
Baliospermum
Black spruce
Blackthorn
Bleeding Heart
Bridges' Penstemon
Black-Eyed Susan
Blackbrush
Brazillian peppertree
Bisabolene
Bloodroot
Benzoin
Begonia fimbristipula
Black Poplar
Bletilla
Barbary matrimony vine
Bush Monkey Flower
Babassu
Black root
Bittersweet
Calochortus
Comfrey
Candleberry
Calotropis gigantea
Cattail
Columbine
Cornflower
Common Thatching grass
Common Zinnia
Cynoglossum grande
Cedar
Campylandra fimbriata
Campsiandra angustifolia
Cranesbill
Chinese Thoroughwax
Carrapichinho
Cedrus libani
Ceanothus integerrimus
Cyanthillium cinereum
Castile Soap
Chiococca alba
Cocklebur
Copaiba Oil
Calyptridium umbellatum
Dragon's Blood
Devil's Club
Dwarf Nettle
Davilla rugosa
Deerbrush
Erigeron
Elephant Vine
European hazel
English Elm
Emu Oil
Elkweed
Eupatorium
Elemi
Oak
Polyvinyl alcohol
Snakeroot (unspecified)
Other health conditions supported by Comfrey
AbrasionsAfterbirth Pain
Bruises (healing)
Burns and Scalds
Cuts
Injuries
Scratches and Abrasions
Ulcerations (external)
Wounds and Sores