Evidence supporting the use of: Anthocyanidins
For the health condition: Rheumatoid Arthritis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Anthocyanidins are a class of flavonoids found in various fruits and vegetables, known for their antioxidant and anti-inflammatory properties. There is emerging scientific evidence supporting their potential role in managing inflammatory conditions such as Rheumatoid Arthritis (RA). Preclinical studies, including in vitro and animal models, have demonstrated that anthocyanidins can inhibit the production of pro-inflammatory cytokines (such as TNF-α and IL-1β) and suppress oxidative stress, both of which are implicated in the pathogenesis of RA. Some small clinical studies and pilot trials have also reported reduced markers of inflammation and modest improvements in symptoms among RA patients consuming anthocyanidin-rich extracts, such as those from cherries or berries.

However, the body of evidence remains limited and is not yet robust. Most human studies are small, short-term, and vary widely in design, making it difficult to draw firm conclusions about efficacy. There are currently no large-scale, high-quality randomized controlled trials definitively establishing anthocyanidins as an effective treatment for RA. Thus, while there is a scientific rationale and some preliminary evidence, the overall strength of the evidence is low, and anthocyanidins should not be considered a primary therapy for RA. Instead, they may be used as adjuncts within a broader anti-inflammatory dietary approach, pending further research.

More about anthocyanidins
More about Rheumatoid Arthritis

Other ingredients used for Rheumatoid Arthritis

adrenal cortex
Alfalfa
algal oil
alpha-linolenic acid (ALA)
alpha-pinene
anthocyanins
ashwagandha
astaxanthin
borage oil
celery
coenzyme Q10 (CoQ10)
turmeric
curcumin
d-alpha tocopherol
DHA (docosahexaenoic acid)
diallyl disulfide (DADS)
dong quai root
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
evening primrose oil
fisetin
fish protein
gamma linolenic acid (GLA)
gamma tocopherol
genistein
ginger
green-lipped mussel
krill oil
luteolin
Methylsulfonylmethane (MSM)
Myristoleate
omega-3 fatty acids
phospholipids
resveratrol
rose hips
slippery elm bark
sulforaphane glucosinolate
Urolithin A
vitamin B6
vitamin C
vitamin D
vitamin D3
Watercress
white willow
alpinia galangal
smilax
Fumaria parviflora
Szechuan lovage
amber
teasel
guelder rose
Gentiana macrophylla
Abies spectabilis
AMP-activated protein kinase (AMPK)
clematis
15,16-Dihydrotanshinone I
Aralia
Akebia
antler
apigenin
Abrus
andrographolide
amentoflavone
alpha-lipoic acid
anthocyanidins
ampelopsin
Actaea spicata
arjunic acid
apocynin
arctiin
astragalin
Boswellic Acid
baicalein
bogbean
Boswellia
Black willow
barbasco
bovine cartilage / glycosaminoglycan
baicalin
Black Hellebore
bee venom
Bergenia
cod liver oil
cortisol
Clerodendrum phlomidis
cyanidin
Chinese fleeceflower
Chinese pond turtle
chuchuhuasi
Cetylated Fatty Acids
C-phycocyanin
cannabidiol
carnosic acid
docosahexaenoic Acid
Dihomo-gamma-linolenic acid
Eicosatetraenoic acid
eicosapentaenoic acid
evening primrose oil
fat liver oil
fructoborate
Flemingia philippinensis
frankincense
flavanols
flavones
ginkgetin
Gypenoside
horse gram
Hyperoside
Hellebore
hydroxytyrosol
Harpagoside
Jatropha macrantha
Kaempferol
mangiferin
Myricetin
madder
Marine fat
Nobiletin
Osthole
Puerarin
Piper chaba
Phaeophyceae
proteoglycans
Polydatin
polyunsaturated fat
Palmitoylethanolamide (PEA)
Qin Jiao
Silkmoth
Schizochytrium Oil
Schizochytrium
Salicin
Salmon Oil
Salvianolic acid
Sinomenium acutum
Semecarpus anacardium
saponins
Shilajit
Stearidonic acid
Sulforaphane
Taxillus chinensis
Tanshinone
Uncaria
Ursolic Acid
Withanolides

Products containing anthocyanidins

We currently have no products on Caring Sunshine that contain this ingredient.