Selenium yeast is a supplement form of selenium, an essential trace mineral known to play significant roles in human health, including the reproductive system. Scientific validation for its use in reproductive health primarily comes from studies on selenium’s biological functions and observational data linking selenium status to reproductive outcomes. Selenium is a critical component of selenoproteins, such as glutathione peroxidases, which protect cells from oxidative damage. This antioxidant property is particularly important in reproductive tissues, where oxidative stress can impair gamete quality and fertility.

In males, selenium supplementation (often as selenium yeast) has been shown in some clinical and animal studies to improve sperm motility and morphology, and it may reduce oxidative damage in semen. Some randomized controlled trials have reported benefits in male fertility parameters, particularly when selenium is combined with other antioxidants. In females, selenium is involved in hormone metabolism and may influence ovarian function, but direct evidence from high-quality human studies is limited.

While selenium yeast is a bioavailable and safe form of selenium, the evidence supporting its targeted use for reproductive support is moderate, with most benefits seen in populations with low selenium status. Excess intake can be harmful, so supplementation should be approached cautiously. Overall, there is scientific rationale and some clinical evidence for selenium yeast supporting reproductive health, particularly in men, but more large-scale, well-controlled studies are needed.