Evidence supporting the use of: Polyethylene glycol
For the body system: Rectum

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Polyethylene glycol (PEG) is scientifically validated for use in supporting the rectum and lower gastrointestinal (GI) tract, specifically as a laxative for the treatment of constipation. PEG is an osmotic agent that works by retaining water in the stool, resulting in softer stools and increased bowel movements, which directly benefits rectal evacuation. Numerous clinical trials and systematic reviews have demonstrated the efficacy and safety of PEG in both adults and children with functional constipation. PEG is commonly recommended in clinical guidelines as a first-line therapy for chronic constipation and for bowel preparation prior to diagnostic procedures such as colonoscopy. The evidence base includes placebo-controlled randomized trials showing significant improvements in stool frequency, consistency, and ease of passage compared to placebo and other laxatives. Its use is not based on tradition but on a well-understood mechanism of action and robust clinical data. Adverse effects are generally mild and include bloating, flatulence, and occasional diarrhea. Overall, PEG is a cornerstone in the management of constipation and rectal evacuation disorders, with a strong scientific foundation supporting its use in the rectal body system.

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Products containing Polyethylene glycol

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