Evidence supporting the use of: Unsaturated fatty acid
For the health condition: Psoriasis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Unsaturated fatty acids, particularly omega-3 and omega-6 polyunsaturated fatty acids (PUFAs), have been investigated for their potential role in supporting or treating psoriasis. Scientific interest in these compounds arises from their known anti-inflammatory properties. Psoriasis is a chronic, immune-mediated skin disorder characterized by inflammation and hyperproliferation of keratinocytes. Several clinical trials and meta-analyses have examined the effects of dietary supplementation with unsaturated fatty acids, especially omega-3 fatty acids from fish oil, on psoriasis severity.

Evidence suggests that omega-3 PUFAs may reduce the production of pro-inflammatory cytokines (such as TNF-α and IL-1β) and modulate immune cell function, which are relevant mechanisms in psoriasis pathogenesis. Some randomized controlled trials (RCTs) have reported modest improvements in Psoriasis Area and Severity Index (PASI) scores, scaling, and erythema following omega-3 supplementation. However, results across studies remain mixed: some RCTs show clear benefit, while others report minimal or no effect compared to placebo. Systematic reviews (e.g., Cochrane reviews) generally conclude that while there is a plausible biological rationale and some supportive evidence, the overall quality and consistency of the data is moderate and further robust trials are needed.

In summary, scientific evidence supports a possible benefit of unsaturated fatty acids, particularly omega-3 PUFAs, in psoriasis, but the effect size appears modest, and routine use is not universally endorsed by major dermatological guidelines at this time.

More about Unsaturated fatty acid
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Other ingredients used for Psoriasis

alfalfa
algal oil
aloe vera
alpha-linolenic acid (ALA)
Beta-Glucan
bifidobacterium breve
bifidobacterium longum
black currant
black walnut
bupleurum falcatum
burdock
butyrate triglyceride
Chinese salvia root
turmeric
curcumin
d-alpha tocopherol
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish protein
gamma linolenic acid (GLA)
gooseberry
gotu kola
green tea
hyaluronic acid
knotweed
lactiplantibacillus plantarum
lactobacillus rhamnosus
lactobacillus salivarius
linoleic acid (LA)
luteolin
magnesium
marshmallow
mixed carotenoids
nettle
niacinamide (vitamin B3)
oleanolic acid
olive
omega-3 fatty acids
omega-6 fatty acids
perilla
phospholipids
pomegranate
quercetin
resveratrol
specialized pro-resolving mediators (SPMs)
spirulina
vitamin A
vitamin D
vitamin D3
vitamin E
seaweed
wheat grass
mulberry
zinc
sarsaparilla
rubia cordifolia
lingzhi
morus
sunflower
ferulic acid
birch
melaleuca alternifolia
AMP-activated protein kinase (AMPK)
Apple Cider Vinegar
Apigenin
Andrographolide
Avocado
Alpha Hydroxy Acids
Aureobasidium pullulans
Andrographis
Agrimonia pilosa
Argan nut oil
Astragalin
Bee Propolis
Baikal Skullcap
Babchi
Baphicacanthus cusia
Boswellic Acid
Barleria
Baicalein
Boswellia
Banyan
Borassus aethiopum
Baicalin
Caffeic Acid
Centella triterpenes
Cod Liver Oil
Cnidium
Centella asiatica
Cistus
Chirata
Cannabidiol
Copaiba Oil
Docosahexaenoic Acid
European Elder
Emu Oil
Eicosapentaenoic Acid
Ethyl Linoleate
Fumaric Acid
Ficus religiosa
Frankincense
Gallic Acid
Glycolic acid
Glucosylceramide
Glycyrrhetinic Acid
Glycyrrhizin
vegetable oil
walnut

Products containing Unsaturated fatty acid

We currently have no products on Caring Sunshine that contain this ingredient.