Evidence supporting the use of: Triterpene Saponin
For the health condition: Psoriasis
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Triterpene saponins are a diverse class of naturally occurring compounds found in many medicinal plants, such as Glycyrrhiza glabra (licorice), Centella asiatica, and Panax ginseng. Historically, extracts from these plants have been used in various traditional medicine systems—including Traditional Chinese Medicine and Ayurveda—for the treatment of inflammatory skin conditions, including psoriasis. The traditional use is based on the observed anti-inflammatory, immunomodulatory, and wound-healing properties of these plant extracts. For example, licorice root, rich in triterpene saponins (notably glycyrrhizin), has long been used topically and orally for skin ailments. However, direct scientific evidence supporting the use of isolated triterpene saponins for psoriasis is limited. Most available research consists of in vitro or animal studies demonstrating anti-inflammatory effects, inhibition of pro-inflammatory cytokines, and antioxidant activity. Some studies suggest these mechanisms could be relevant to psoriasis, but robust clinical trials in humans are lacking. Therefore, while triterpene saponin-containing herbs have a traditional role in managing psoriasis and related skin disorders, scientific validation for their efficacy and safety specifically in psoriasis is not well established. The evidence supporting their use is thus rated as limited (2/5), relying on traditional practice and preliminary scientific rationale rather than definitive clinical proof.
Other ingredients used for Psoriasis
alfalfaalgal oil
aloe vera
alpha-linolenic acid (ALA)
Beta-Glucan
bifidobacterium breve
bifidobacterium longum
black currant
black walnut
bupleurum falcatum
burdock
butyrate triglyceride
Chinese salvia root
turmeric
curcumin
d-alpha tocopherol
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish protein
gamma linolenic acid (GLA)
gooseberry
gotu kola
green tea
hyaluronic acid
knotweed
lactiplantibacillus plantarum
lactobacillus rhamnosus
lactobacillus salivarius
linoleic acid (LA)
luteolin
magnesium
marshmallow
mixed carotenoids
nettle
niacinamide (vitamin B3)
oleanolic acid
olive
omega-3 fatty acids
omega-6 fatty acids
perilla
phospholipids
pomegranate
quercetin
resveratrol
specialized pro-resolving mediators (SPMs)
spirulina
vitamin A
vitamin D
vitamin D3
vitamin E
seaweed
wheat grass
mulberry
zinc
sarsaparilla
rubia cordifolia
lingzhi
morus
sunflower
ferulic acid
birch
melaleuca alternifolia
AMP-activated protein kinase (AMPK)
Apple Cider Vinegar
Apigenin
Andrographolide
Avocado
Alpha Hydroxy Acids
Aureobasidium pullulans
Andrographis
Agrimonia pilosa
Argan nut oil
Astragalin
Bee Propolis
Baikal Skullcap
Babchi
Baphicacanthus cusia
Boswellic Acid
Barleria
Baicalein
Boswellia
Banyan
Borassus aethiopum
Baicalin
Caffeic Acid
Centella triterpenes
Cod Liver Oil
Cnidium
Centella asiatica
Cistus
Chirata
Cannabidiol
Copaiba Oil
Docosahexaenoic Acid
European Elder
Emu Oil
Eicosapentaenoic Acid
Ethyl Linoleate
Fumaric Acid
Ficus religiosa
Frankincense
Gallic Acid
Glycolic acid
Glucosylceramide
Glycyrrhetinic Acid
Glycyrrhizin
vegetable oil
walnut
Other health conditions supported by Triterpene Saponin
Cancer (natural therapy for)Cancer (prevention)
Cancer Treatment (reducing side effects)
Cholesterol (high)
Circulation (poor)
Diabetes
Fatigue
Gastritis
Hepatitis
Hypertension
Inflammation
Liver Detoxification
Memory and Brain Function
Psoriasis
Ulcers
Urinary Tract Infections